How do environmental factors influence life cycles and development? An experimental framework for early-diverging metazoans.
How do environmental factors influence life cycles and development? An experimental framework for early-diverging metazoans.
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DOI：
10.1002/bies.201400065
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发表时间：
2014-12
期刊：
影响因子：
4
通讯作者：
Miller, David J.
中科院分区：
文献类型：
--
作者：
Bosch, Thomas C. G.;Adamska, Maja;Augustin, Rene;Domazet-Loso, Tomislav;Foret, Sylvain;Fraune, Sebastian;Funayama, Noriko;Grasis, Juris;Hamada, Mayuko;Hatta, Masayuki;Hobmayer, Bert;Kawai, Kotoe;Klimovich, Alexander;Manuel, Michael;Shinzato, Chuya;Technau, Uli;Yum, Seungshic;Miller, David J.
生态发育生物学（eco-devo）研究个体发育过程与环境因素之间的机制关系。最近的研究表明，其中一些关系具有深刻的进化起源，甚至可能早于现存最简单的动物（包括刺胞动物和海绵动物）的分化。这些早期分化的后生动物的发育通常对环境因素很敏感，这些相互作用发生在保守的信号通路和组织稳态机制的背景下，其详细的分子逻辑仍然难以捉摸。刺胞动物转基因的有效方法，以及在刺胞动物和海绵中易于操作的实验，使它们成为理解环境因素与发育机制之间因果关系的理想模型。在这里，我们确定了动物进化和发育之间的主要问题，并概述了旨在确定早期分化后生动物中将环境因素与发育机制联系起来的机制的研究路线图。
Ecological developmental biology (eco-devo) explores the mechanistic relationships between the processes of individual development and environmental factors. Recent studies imply that some of these relationships have deep evolutionary origins, and may even predate the divergences of the simplest extant animals, including cnidarians and sponges. Development of these early diverging metazoans is often sensitive to environmental factors, and these interactions occur in the context of conserved signaling pathways and mechanisms of tissue homeostasis whose detailed molecular logic remain elusive. Efficient methods for transgenesis in cnidarians together with the ease of experimental manipulation in cnidarians and sponges make them ideal models for understanding causal relationships between environmental factors and developmental mechanisms. Here, we identify major questions at the interface between animal evolution and development and outline a road map for research aimed at identifying the mechanisms that link environmental factors to developmental mechanisms in early diverging metazoans.
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影响因子：
4
作者：
Fraune, Sebastian;Bosch, Thomas C. G.
通讯作者：
Bosch, Thomas C. G.
影响因子：
2.6
作者：
Carla', EC;Pagliara, P;Dini, L
通讯作者：
Dini, L
影响因子：
2.5
作者：
Arnold, Suzanne N.;Steneck, Robert S.;Mumby, Peter J.
通讯作者：
Mumby, Peter J.
影响因子：
6.6
作者：
Boettger, Angelika;Strasser, Dominik;David, Charles N.
通讯作者：
David, Charles N.
DOI：
10.1016/s0022-0981(00)00209-4
发表时间：
2000-08-23
影响因子：
2
作者：
Baird, AH;Hughes, TP
通讯作者：
Hughes, TP