Role of ferroptosis in neurological diseases
Role of ferroptosis in neurological diseases
复制标题
铁死亡在神经系统疾病中的作用
DOI:
10.1016/j.neulet.2020.135614
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发表时间:
2021-01
影响因子:
2.5
通讯作者:
Gao Jing
中科院分区:
文献类型:
--
作者:
Yao Min-Yi;Liu Tao;Zhang Liang;Wang Ming-Jian;Yang Yong;Gao Jing
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD) characterized by iron-dependent accumulation of lipid peroxides which leads to oxidative stress and cell death. Recent studies have indicated that ferroptosis plays an essential role in the pathology of neurological diseases, such as intracerebral hemorrhage, ischemic stroke, epilepsy, neurodegenerative diseases, traumatic brain injury and brain cancer. This review focuses on the latest researches on the relationship of ferroptosis with nervous system diseases, highlighting the ferroptosis-based mechanisms, and elaborating the new perspective therapeutic targets of neurological disorders.
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影响因子:
2.6
作者:
Qing Ye;Chunmei Zeng;Chun Luo;Yuan Wu
通讯作者:
Qing Ye;Chunmei Zeng;Chun Luo;Yuan Wu
影响因子:
25
作者:
Staley, Kevin
通讯作者:
Staley, Kevin
影响因子:
14.8
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Bayır H
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64.5
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Dixon SJ;Lemberg KM;Lamprecht MR;Skouta R;Zaitsev EM;Gleason CE;Patel DN;Bauer AJ;Cantley AM;Yang WS;Morrison B 3rd;Stockwell BR
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Stockwell BR
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11.2
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Karuppagounder SS;Alin L;Chen Y;Brand D;Bourassa MW;Dietrich K;Wilkinson CM;Nadeau CA;Kumar A;Perry S;Pinto JT;Darley-Usmar V;Sanchez S;Milne GL;Pratico D;Holman TR;Carmichael ST;Coppola G;Colbourne F;Ratan RR
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Ratan RR