Understanding synapses: past, present, and future.
Understanding synapses: past, present, and future.
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DOI:
10.1016/j.neuron.2008.10.011
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发表时间:
2008-11-06
期刊:
影响因子:
16.2
通讯作者:
Malenka RC
中科院分区:
文献类型:
--
作者:
Südhof TC;Malenka RC
Classical physiological work by Katz, Eccles, and others revealed the central importance of synapses in brain function, and characterized the mechanisms involved in synaptic transmission. Building on this work, major advances in the past two decades have elucidated how synapses work molecularly. In the present perspective, we provide a short description of our personal view of these advances, suggest a series of important future questions about synapses, and discuss ideas about how best to achieve further progress in the field.
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