Complexity of desire for hastened death in terminally ill cancer patients: A cluster analysis
Complexity of desire for hastened death in terminally ill cancer patients: A cluster analysis
复制标题
癌症晚期患者加速死亡愿望的复杂性：聚类分析
DOI：
10.1017/s1478951521000080
复制
发表时间：
2021
影响因子：
2.2
通讯作者：
on behalf of the EASED Investigators
中科院分区：
文献类型：
--
作者：
Hatano Yutaka;Morita Tatsuya;Mori Masanori;Maeda Isseki;Oyamada Shunsuke;Naito Akemi Shirado;Oya Kiyofumi;Sakashita Akihiro;Ito Satoko;Hiratsuka Yusuke;Tsuneto Satoru;on behalf of the EASED Investigators
ObjectivesThe本研究的目的是（1）确定接受专门姑息治疗的渴望加速死亡（DHD）的晚期癌症患者的比例，（2）确定DHD的原因，（3）将DHD患者分为一些可解释的亚组。数据由主要负责医生前瞻性获取。记录DHD的存在/不存在以及DHD的原因。进行聚类分析，以确定DHD.ResultsData从971例患者，其里士满躁动镇静量表评分入院时为零，谁死在姑息治疗单位的亚组模式进行了分析。平均年龄为72岁，常见的原发癌部位为胃肠道（31%）和肝/胆管/胰腺（19%）。共有174例患者（18%：95%置信区间，16-20）表达DHD。DHD的常见原因是依赖（45%），对他人的负担（28%），无意义（24%）和无法从事愉快的活动（24%）。我们确定了五组DHD患者：第1组（35%，61/173）：“身体不适”，第2类（21%，37/173）：“依赖和负担沉重”，第3类（19%，33/173）：“绝望”，第4类（17%，30/173）：“严重疲劳”，第5类（7%，12/173）：“广泛的生存痛苦”。结论DHD患者中有相当一部分患者表现为DHD，并可分为5个亚组。这些发现可能有助于治疗策略的发展。
ObjectivesThe present study aims were (1) to identify the proportion of terminally ill cancer patients with desire for hastened death (DHD) receiving specialized palliative care, (2) to identify the reasons for DHD, and (3) to classify patients with DHD into some interpretable subgroups.MethodsAdvanced cancer patients admitted to 23 inpatients hospices/palliative care units in 2017 were enrolled. Data were prospectively obtained by the primarily responsible physicians. The presence/absence of DHD and reasons for DHD were recorded. A cluster analysis was performed to identify patterns of subgroups in patients with DHD.ResultsData from 971 patients, whose Richmond Agitation–Sedation Scale score at admission was zero and who died in palliative care units, were analyzed. The average age was 72 years, common primary cancer sites were the gastrointestinal tract (31%) and the liver/biliary ducts/pancreas (19%). A total of 174 patients (18%: 95% confidence interval, 16–20) expressed DHD. Common reasons for DHD were dependency (45%), burden to others (28%), meaninglessness (24%), and inability to engage in pleasant activities (24%). We identified five clusters of patients with DHD: cluster 1 (35%, 61/173): “physical distress,” cluster 2 (21%, 37/173): “dependent and burdensome,” cluster 3 (19%, 33/173): “hopelessness,” cluster 4 (17%, 30/173): “profound fatigue,” and cluster 5 (7%, 12/173): “extensive existential suffering.”ConclusionsA considerable number of patients expressed DHD and could be categorized into five subgroups. These findings may contribute to the development of therapeutic strategies.
登录
查看更多内容
绝症癌症患者对安乐死和协助自杀的态度：心理社会决定因素和信念对症状困扰和随后的生存的主导作用。
影响因子：
45.3
作者：
M. Suarez‐Almazor;C. Newman;J. Hanson;E. Bruera
通讯作者：
E. Bruera
DOI：
10.1136/bmj.a1682
发表时间：
2008-10-07
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Ganzini L;Goy ER;Dobscha SK
通讯作者：
Dobscha SK
晚期癌症患者的生理和心理因素以及加速死亡的愿望
影响因子：
3.6
作者：
Christian Villavicencio;C. Monforte;Joaquín Tomás;Markus A. Maier;J. Porta;A. Balaguer
通讯作者：
A. Balaguer
影响因子：
4.7
作者：
Yao, Chien-An;Hu, Wen-Yu;Chiu, Tai-Yuan
通讯作者：
Chiu, Tai-Yuan
影响因子：
3.4
作者：
Chochinov, HM;Wilson, KG;Lander, S
通讯作者：
Lander, S