Realization and efficiency evaluation of a micro-photocatalytic cell prototype for real-time blood oxygenation.

Realization and efficiency evaluation of a micro-photocatalytic cell prototype for real-time blood oxygenation.
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DOI:
10.1016/j.medengphy.2010.10.008
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发表时间:
2011-09
影响因子:
2.2
通讯作者:
Thorsen TA
Thorsen TA
中科院分区:
工程技术3区
文献类型:
--
作者:
Rasponi M;Ullah T;Gilbert RJ;Fiore GB;Thorsen TA

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本研究设计并验证了一种新型的、小型化的、高效的光催化电池,能够在动态条件下工作。微流体通道通过标准的软光刻技术由聚二甲基硅氧烷(PDMS)模制而成,以便用作光催化电池,其中可固化的二氧化钛薄膜和铂电极的耦合允许电辅助的光催化反应以从流动流体(例如血液)的水含量产生溶解的氧气。在室温(300 K)下,采用反应性射频溅射法,以钛金属为靶材,在石英玻璃衬底上制备了薄膜。通过亚甲基蓝溶液的还原率评价了其光催化活性。作为概念验证,当前研究的结果表明,该器械可以以4.06μM O2/(cm 2 min)的速率产生氧气,从而将其可能的应用范围扩展到流动静脉血的完全氧合。
A novel, miniaturized, high-efficiency photocatalytic cell, able to work in dynamic conditions, has been designed and validated in this study. Microfluidic channels were molded out of polydimethylsiloxane (PDMS) by means of standard soft lithography techniques, so as to work as photocatalytic cells, where the coupling of anatase titanium dioxide thin films and platinum electrodes, allows an electrically assisted photocatalytic reaction to produce dissolved oxygen gas from the water content of flowing fluid (e.g. blood). The thin films were deposited onto quartz glass substrates at room temperature (300K) using reactive radio-frequency sputtering with a titanium metal target. The photocatalytic activity was evaluated through reduction rate of methylene blue solution. The results of the current study, as a proof of concept, have shown that the device can generate oxygen at a rate of 4.06μM O2/(cm2 min), thus extending its possible application range to the full oxygenation of flowing venous blood.
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