Timing without coding: How do long non-coding RNAs regulate circadian rhythms?
Timing without coding: How do long non-coding RNAs regulate circadian rhythms?
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DOI:
10.1016/j.semcdb.2021.04.020
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发表时间:
2022-06
影响因子:
7.3
通讯作者:
Kojima S
中科院分区:
文献类型:
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作者:
Mosig RA;Kojima S
Long non-coding RNAs (lncRNAs) are a new class of regulatory RNAs that play important roles in disease development and a variety of biological processes. Recent studies have underscored the importance of lncRNAs in the circadian clock system and demonstrated that lncRNAs regulate core clock genes and the core clock machinery in mammals. In this review, we provide an overview of our current understanding of how lncRNAs regulate the circadian clock without coding a protein. We also offer additional insights into the challenges in understanding the functions of lncRNAs and other unresolved questions in the field. We do not cover other regulatory ncRNAs even though they also play important roles; readers are highly encouraged to refer to other excellent reviews on this topic.
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影响因子:
5.6
作者:
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通讯作者:
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DOI:
10.1126/science.1198125
发表时间:
2011-03-11
期刊:
Science (New York, N.Y.)
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影响因子:
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作者:
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通讯作者:
Rinn, John L.
影响因子:
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