Surface properties of modified nanosized silica and their influence on human serum albumin immobilization

Surface properties of modified nanosized silica and their influence on human serum albumin immobilization
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改性纳米二氧化硅的表面性质及其对人血清白蛋白固定化的影响

DOI:
10.1134/s2070205110050072
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发表时间:
2010
影响因子:
1.1
通讯作者:
E. Parfenyuk
E. Parfenyuk
中科院分区:
材料科学4区
文献类型:
--
作者:
G. A. Kulikova;E. Parfenyuk

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采用溶胶-凝胶法制备了不同表面官能团的SiO2粉体。红外光谱证实了二氧化硅表面官能团的引入。利用BET法测定了二氧化硅颗粒的表面物理参数(比表面积、孔径、孔形状和孔体积)。研究了合成粉体对人血清白蛋白的吸附性能。使用原子力显微镜,我们确定了吸附蛋白质的二氧化硅颗粒的大小。推测二氧化硅颗粒表面性质对吸附蛋白质的量的影响。
Silica powders with different surface functional groups were synthesized using the sol-gel method. The introduction of functional groups on the surface of silica was confirmed by IR spectroscopy. Surface physical parameters of silica particles (specific surface area, pore size, pore shape and volume) were obtained using BET. We have studied the adsorption capacity of human serum albumin on synthesized powders. Using atomic-force microscopy, we determined the size of silica particles with adsorbed protein. The influence of silica particle surface properties on the amount of adsorbed protein is speculated.
DOI: 10.1016/j.biomaterials.2008.02.026
发表时间: 2008-06
期刊: Biomaterials
影响因子: 14
作者:
B. Menaa;M. Herrero;V. Rives;M. Lavrenko;D. Eggers
通讯作者: B. Menaa;M. Herrero;V. Rives;M. Lavrenko;D. Eggers