Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling.
Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling.
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DOI：
10.1016/j.semcdb.2012.08.011
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发表时间：
2012-10
影响因子：
7.3
通讯作者：
Rendl, Michael
中科院分区：
文献类型：
--
作者：
Sennett, Rachel;Rendl, Michael
胚胎毛囊的诱导和形成受到特化真皮细胞和表皮干细胞之间间充质-上皮相互作用的调节，从而转变为头发的命运。同样，在出生后毛发生长过程中，间充质真皮乳头细胞与周围上皮基质细胞之间的通讯协调毛干的产生。毛发周期中的成年毛囊再生再次被认为是通过激活源自间充质室并作用于毛囊干细胞的信号来控制的。尽管许多信号通路与毛囊的形成和生长有关，但这些诱导信号和调节信号的确切性质、时间和交叉仍然难以捉摸。本综述的目的是总结我们目前的理解，并讨论毛囊形态发生和循环过程中间充质-上皮相互作用的最新见解。
Embryonic hair follicle induction and formation are regulated by mesenchymal-epithelial interactions between specialized dermal cells and epidermal stem cells that switch to a hair fate. Similarly, during postnatal hair growth, communication between mesenchymal dermal papilla cells and surrounding epithelial matrix cells coordinates hair shaft production. Adult hair follicle regeneration in the hair cycle again is thought to be controlled by activating signals originating from the mesenchymal compartment and acting on hair follicle stem cells. Although many signaling pathways are implicated in hair follicle formation and growth, the precise nature, timing, and intersection of these inductive and regulatory signals remains elusive. The goal of this review is to summarize our current understanding and to discuss recent new insights into mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling.
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影响因子：
2.7
作者：
Chiang, C;Swan, RZ;Dlugosz, AA
通讯作者：
Dlugosz, AA
影响因子：
4.6
作者：
Croyle, Mandy J.;Lehman, Jonathan M.;Yoder, Bradley K.
通讯作者：
Yoder, Bradley K.
影响因子：
4
作者：
Alonso, L;Fuchs, E
通讯作者：
Fuchs, E
DOI：
10.1073/pnas.1006437108
发表时间：
2011-08-02
影响因子：
11.1
作者：
Barrott, Jared J.;Cash, Gabriela M.;Murtaugh, L. Charles
通讯作者：
Murtaugh, L. Charles
影响因子：
6.5
作者：
Botchkarev, VA;Botchkareva, NV;Gilchrest, BA
通讯作者：
Gilchrest, BA