Multi-scale model of clogging in microfluidic devices with grid-like geometries
Multi-scale model of clogging in microfluidic devices with grid-like geometries
复制标题
网格状微流体装置堵塞的多尺度模型
DOI:
10.1098/rspa.2022.0119
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Fai, Thomas G.
中科院分区:
文献类型:
--
作者:
Kelly, Gess;Fai, Thomas G.
We propose a coarse-grained theoretical model to capture the ageing of microfluidic devices under different conditions including constant applied flow rate and constant applied pressure gradient. Microfluidic devices that sort cells by their deformability hold significant promise for medical applications. However, clogging in these microfluidic systems causes their properties to change over time and potentially limits their reliability. We compare the results of the coarse-grained model with those of stochastic simulations and with existing theoretical studies. Lastly, we apply the model to experimental data on the clogging of sickle red blood cells and discuss its wider applicability.
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DOI:
10.1007/978-0-387-48807-3_46
发表时间:
2008
期刊:
2013 Proceedings IEEE INFOCOM
影响因子:
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作者:
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通讯作者:
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DOI:
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发表时间:
2014-05
期刊:
Physical review. E, Statistical, nonlinear, and soft matter physics
影响因子:
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作者:
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通讯作者:
R. Kusters;Thijs W. G. van der Heijden;B. Kaoui;J. Harting;C. Storm
影响因子:
3.4
作者:
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通讯作者:
Fabry, Ben
影响因子:
15.9
作者:
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通讯作者:
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DOI:
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发表时间:
1996
期刊:
影响因子:
--
作者:
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通讯作者:
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