Lights and Shadows in Hepatic Encephalopathy Diagnosis.
Lights and Shadows in Hepatic Encephalopathy Diagnosis.
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DOI：
10.3390/jcm10020341
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发表时间：
2021-01-18
影响因子：
3.9
通讯作者：
Montagnese S
中科院分区：
文献类型：
--
作者：
Amodio P;Montagnese S
肝性脑病（HE）是一种由肝功能不全和/或门静脉-全身分流引起的脑功能障碍。高等教育的确切性质存在争议；因此，术语“HE”的冲突使用可能导致其检测和管理的不一致。本文将根据“HE”一词的历史渊源和当前共识，对其含义进行梳理。它还根据其表型和发生的危险因素提供了诊断条件的标准。从导致相似表型的其他条件中进行鉴别诊断的程序，连同沉淀剂和混杂因素被考虑在内。最后，讨论了当前正确临床报告HE发作的多维方法。
Hepatic encephalopathy (HE) is a form of brain dysfunction that is caused by liver insufficiency and/or portal-systemic shunting. The exact nature of HE is debated; as such, conflicting uses of the term “HE” may cause inconsistencies in its detection and management. This review highlights the meaning of the term “HE” on the basis of its historical origins and current consensus. It also provides criteria for the diagnosis of the condition based on its phenotypes and risk factors for its occurrence. The procedure for differential diagnosis from other conditions which result in similar phenotypes is considered, together with precipitants and confounders. Finally, the current multidimensional approach for the correct clinical reporting of HE episodes is discussed.
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