Megascience. 'Omics data sharing.
Megascience. 'Omics data sharing.
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DOI：
10.1126/science.1180598
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发表时间：
2009-10-09
期刊：
影响因子：
--
通讯作者：
Wilbanks J
中科院分区：
文献类型：
--
作者：
Field D;Sansone SA;Collis A;Booth T;Dukes P;Gregurick SK;Kennedy K;Kolar P;Kolker E;Maxon M;Millard S;Mugabushaka AM;Perrin N;Remacle JE;Remington K;Rocca-Serra P;Taylor CF;Thorley M;Tiwari B;Wilbanks J
高通量基因组学和后基因组学技术的发展引起了数据处理和加工方法的变化。一个生物样本可以用来并行生成多种“大”数据，如基因组序列（基因组学）、基因和蛋白质表达模式（转录组学和蛋白质组学）以及代谢物浓度和通量（代谢组学）。即使对这些数据进行基本分析也需要大量的计算机操作;当必须比较或综合两项或两项以上研究的产出时，挑战就更大了。
Development of high-throughput genomic and postgenomic technologies has caused a change in approaches to data handling and processing . One biological sample might be used to generate many kinds of “big” data in parallel, such as genome sequence (genomics), patterns of gene and protein expression (transcriptomics and proteomics), and metabolite concentrations and fluxes (metabolomics). Extensive computer manipulations are required for even basic analyses of such data; the challenges mount further when two or more studies' outputs must be compared or integrated.
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影响因子：
64.8
作者：
通讯作者：
--
影响因子：
46.9
作者：
Smith, Barry;Ashburner, Michael;Lewis, Suzanna
通讯作者：
Lewis, Suzanna
影响因子：
46.9
作者：
Taylor, Chris F.;Field, Dawn;Sansone, Susanna-Assunta;Aerts, Jan;Apweiler, Rolf;Ashburner, Michael;Ball, Catherine A.;Binz, Pierre-Alain;Bogue, Molly;Booth, Tim;Brazma, Alvis;Brinkman, Ryan R.;Clark, Adam Michael;Deutsch, Eric W.;Fiehn, Oliver;Fostel, Jennifer;Ghazal, Peter;Gibson, Frank;Gray, Tanya;Grimes, Graeme;Hancock, John M.;Hardy, Nigel W.;Hermjakob, Henning;Julian, Randall K., Jr.;Kane, Matthew;Kettner, Carsten;Kinsinger, Christopher;Kolker, Eugene;Kuiper, Martin;Le Novere, Nicolas;Leebens-Mack, Jim;Lewis, Suzanna E.;Lord, Phillip;Mallon, Ann-Marie;Marthandan, Nishanth;Masuya, Hiroshi;McNally, Ruth;Mehrle, Alexander;Morrison, Norman;Orchard, Sandra;Quackenbush, John;Reecy, James M.;Robertson, Donald G.;Rocca-Serra, Philippe;Rodriguez, Henry;Rosenfelder, Heiko;Santoyo-Lopez, Javier;Scheuermann, Richard H.;Schober, Daniel;Smith, Barry;Snape, Jason;Stoeckert, Christian J., Jr.;Tipton, Keith;Sterk, Peter;Untergasser, Andreas;Vandesompele, Jo;Wiemann, Stefan
通讯作者：
Wiemann, Stefan
影响因子：
64.8
作者：
Howe, Doug;Costanzo, Maria;Fey, Petra;Gojobori, Takashi;Hannick, Linda;Hide, Winston;Hill, David P.;Kania, Renate;Schaeffer, Mary;St Pierre, Susan;Twigger, Simon;White, Owen;Rhee, Seung Yon
通讯作者：
Rhee, Seung Yon
影响因子：
46.9
作者：
Jones, Andrew R.;Miller, Michael;Pizarro, Angel
通讯作者：
Pizarro, Angel