Are adverse childhood experiences and depression associated with impaired glucose tolerance in females? An experimental study.
Are adverse childhood experiences and depression associated with impaired glucose tolerance in females? An experimental study.
复制标题
不良的童年经历和抑郁症是否与女性糖耐量受损有关?
DOI:
10.1016/j.jpsychires.2017.07.028
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发表时间:
2017
影响因子:
4.8
通讯作者:
Christian
中科院分区:
文献类型:
--
作者:
Wingenfeld;Linn K;Boeker;Schultebraucks;Katharina;Schulz;Stenzel;Spitzer;Carsten;Christian
Adverse childhood experiences (ACE) enhance the risk for mental disorders, e.g. major depressive disorder (MDD). Increasing evidence suggests an association between ACE and impaired physical health, e.g. metabolic syndrome. The aim of this study was to assess several metabolic risk markers in healthy individuals with and without ACE and depressed patients with and without ACE.We examined glucose and insulin release in the oGTT in 33 women with MDD and ACE, 47 women with MDD without ACE, 21 women with ACE but no current or lifetime MDD and 36 healthy women without either MDD or ACE. Several metabolic markers such as triglycerides, cholesterol, LDL, HDL, HbA1c, BMI and waist to hip ratio were assessed.The four groups did neither differ in insulin release and glucose concentrations in the oGTT nor with respect to other metabolic variables. Depressed patients with and without psychotropic medication did not differ in any outcome variable, but there was a trend towards higher glucose concentrations in the oGTT in patients with current psychotropic medication.In this physically healthy sample neither ACE nor MDD were associated with metabolic risk factors. Thus, metabolic alterations might not directly be linked to ACE and depression.
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DOI:
10.1097/00005053-200110000-00008
发表时间:
2001
期刊:
The Journal of nervous and mental disease
影响因子:
--
作者:
Taylor,RR;Jason,LA
通讯作者:
Jason,LA
影响因子:
8
作者:
Thomas, Claudia;Hyppoenen, Elina;Power, Chris
通讯作者:
Power, Chris
影响因子:
11.3
作者:
Gunstad, John;Paul, Robert H.;Gordon, Evian
通讯作者:
Gordon, Evian
DOI:
--
发表时间:
2010
期刊:
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
影响因子:
--
作者:
Stein,DanJ;Scott,Kate;HaroAbad,JosepM;Aguilar-Gaxiola,Sergio;Alonso,Jordi;Angermeyer,Matthias;Demytteneare,Koen;deGirolamo,Giovanni;Iwata,Noboru;Posada-Villa,José;Kovess,Viviane;Lara,Carmen;Ormel,Johan;Kessler,RonaldC;Von
通讯作者:
Von
影响因子:
4.8
作者:
Bernstein, DP;Stein, JA;Zule, W
通讯作者:
Zule, W