The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation.
The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation.
复制标题
内脏卵黄囊内胚层在神经形成过程中为胚胎提供营养吸收。
DOI：
10.1002/bdra.20705
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Sarkar,AnjaliA
中科院分区：
文献类型：
--
作者：
Zohn,IreneE;Sarkar,AnjaliA
Neural tube defects (NTDs) represent some of the most common congenital malformations in humans. The causes of NTDs are complex with both genetic and environmental contributing factors. Periconception nutrition is an important environmental factor influencing the penetrance of NTDs. NTDs arise from failure to close the neural tube completely during development, an event that occurs before establishment of the chorioallantoic placenta. During neurulation, nutrients are absorbed by histotrophic mechanisms and absorbed by endocytosis in the endoderm‐derived cell layer of the visceral yolk sac (VYS). Here we review the histotrophic mechanisms by which nutrients are delivered to the human embryo during this critical time period. Because more detailed studies on the molecular mechanisms regulating uptake of nutrients have been performed using rodent models, most importantly mouse and rat models, we will also review nutrient uptake in these model organisms to set the stage for presentation of experimental data that have provided valuable information about how nutrients are delivered to the neurulating embryo. Birth Defects Research (Part A), 2010. © 2010 Wiley‐Liss, Inc.
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影响因子：
29
作者：
Donovan, A;Lima, CA;Andrews, NC
通讯作者：
Andrews, NC
影响因子：
30.8
作者：
Aminoff, M;Carter, JE;Krahe, R
通讯作者：
Krahe, R
DOI：
10.1073/pnas.93.16.8612
发表时间：
1996-08-06
影响因子：
11.1
作者：
Moestrup, SK;Birn, H;Nexo, E
通讯作者：
Nexo, E
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影响因子：
3.8
作者：
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通讯作者：
Lloyd,JB
影响因子：
56.9
作者：
BECK, F;LLOYD, JB;GRIFFITHS, A
通讯作者：
GRIFFITHS, A