Factors associated with pain experience outcome in knee osteoarthritis.
Factors associated with pain experience outcome in knee osteoarthritis.
复制标题
DOI：
10.1002/acr.22402
复制
发表时间：
2014-12
影响因子：
4.7
通讯作者：
Sharma, Leena
中科院分区：
文献类型：
--
作者：
Rayahin, Jamie E.;Chmiel, Joan S.;Hayes, Karen W.;Almagor, Orit;Belisle, Laura;Chang, Alison H.;Moisio, Kirsten;Zhang, Yunhui;Sharma, Leena
改善膝关节OA疼痛结局的策略很少，部分原因是如何最好地评估长期疼痛尚不清楚。我们的目标是：基于先前制定的OA疼痛阶段确定良好疼痛体验结局的频率;并检验以下假设：较少的抑郁和疼痛灾难化以及较大的自我效能和社会支持均与良好结局的较大可能性相关。研究参与者均患有膝关节OA，报告了基线和2年时的疼痛分期。基线评估采用老年抑郁量表、疼痛灾难化量表、关节炎自我效能量表和MOS社会支持调查。使用疼痛体验阶段，良好结局定义B 2年时持续或运动至无疼痛或阶段1（可预测的疼痛，已知触发因素）。建立多变量逻辑回归模型以确定良好结局的独立预测因素。在212例患者中，136例（64%）疼痛结局良好，76例（36%）结局不良。在多变量分析中，较高的自我效能与良好结局的可能性显著较高相关（校正OR 1.14，95% CI：1.04-1.24）;较高的疼痛灾难化与良好结局的可能性显著较低相关（校正OR 0.88，95% CI：0.83-0.94）。这种基于分期的测量方法为评估膝关节OA的疼痛结局提供了一种有意义且可解释的方法。膝关节骨性关节炎2年良好结局的几率在疼痛灾难性程度较高的患者中较低，在自我效能较高的患者中较高。针对这些因素可能有助于改善膝关节OA的疼痛结局。
Few strategies to improve pain outcome in knee OA exist, in part because how best to evaluate pain over the long-term is unclear. Our objectives were: determine frequency of a good pain experience outcome based on previously formulated OA pain stages; and test the hypothesis that less depression and pain catastrophizing and greater self-efficacy and social support are each associated with greater likelihood of a good outcome. Study participants all with knee OA reported pain stage at baseline and 2 years. Baseline assessments utilized the Geriatric Depression Scale, Pain Catastrophizing Scale, Arthritis Self-Efficacy Scale, and MOS Social Support Survey. Using pain experience stages, good outcome was defined b persistence in or movement to no pain or stage 1 (predictable pain, known trigger) at 2 years. A multivariable logistic regression model was developed to identify independent predictors of a good outcome. Of 212, 136 (64%) had a good pain outcome and 76 (36%) a poor outcome. In multivariable analysis, higher self-efficacy was associated with a significantly higher likelihood of good outcome (adjusted OR 1.14, 95% CI: 1.04–1.24); higher pain catastrophizing was associated with a significantly lower likelihood of good outcome (adjusted OR 0.88, 95% CI: 0.83–0.94). This stage-based measure provides a meaningful and interpretable means to assess pain outcome in knee OA. The odds of a good 2-year outcome in knee OA were lower in persons with greater pain catastrophizing and higher in persons with greater self-efficacy. Targeting these factors may help to improve pain outcome in knee OA.
登录
查看更多内容
影响因子：
7
作者：
Allen, K. D.;Coffman, C. J.;Keefe, F. J.
通讯作者：
Keefe, F. J.
影响因子：
7
作者：
Allen, K. D.;Oddone, E. Z.;Bosworth, H. B.
通讯作者：
Bosworth, H. B.
影响因子：
7
作者：
Hawker, G. A.;Stewart, L.;Gooberman-Hill, R.
通讯作者：
Gooberman-Hill, R.
影响因子：
7
作者：
Neogi, T.
通讯作者：
Neogi, T.
影响因子：
5.5
作者：
Jinks, C.;Jordan, K. P.;Croft, P.
通讯作者：
Croft, P.