Immunological and gadolinium‐DTPA MRI evaluation of relapsing remitting multiple sclerosis
Immunological and gadolinium‐DTPA MRI evaluation of relapsing remitting multiple sclerosis
复制标题
复发缓解型多发性硬化症的免疫学和钆-DTPA MRI评估
DOI：
10.1111/j.1600-0404.1992.tb05098.x
复制
发表时间：
1992
影响因子：
3.5
通讯作者：
R. Moretti
中科院分区：
文献类型：
--
作者：
R. Capra;N. Marcianô;V. Cotti Cometti;L. Vignolo;M. Bettinzioli;P. Airó;R. Cattaneo;R. Gasparotti;R. Moretti
The levels of lymphocytes, blood lymphocytes subsets (CD3+, CD4+, CD8+, DR+, CD25+, CD4+, CD45RA+, CD4+, CD29+ cells) and sIL‐2r of 10 patients affected by relapsing‐remitting multiple sclerosis were serially studied. The identification of the activity of the disease was made by gadolinium‐DTPA (Gd‐DTPA) MRI. The immunological determinations and the MRI of the brain and spinal cord were performed every 14th day for a period of three months. No significant difference of the immunological values were found between the presence and the absence of Gd‐DTPA enhancing areas, except lymphocytes (p < 0.05). These immunological parameters, evaluated in the peripheral blood, are not a marker of disease activity in relapsing‐remitting MS patients.
进行性多发性硬化症中抑制-诱导 T 细胞亚群的选择性丧失。
DOI：
10.1056/nejm198701083160202
发表时间：
1987
期刊：
The New England journal of medicine
影响因子：
--
作者：
Morimoto,C;Hafler,DA;Weiner,HL;Letvin,NL;Hagan,M;Daley,J;Schlossman,SF
通讯作者：
Schlossman,SF