Liver volume measurement: reason of the difference between in vivo CT-volumetry and intraoperative ex vivo determination and how to cope it.
Liver volume measurement: reason of the difference between in vivo CT-volumetry and intraoperative ex vivo determination and how to cope it.
复制标题
肝脏体积测量：体内CT体积测定与术中离体测定之间差异的原因以及如何应对。
DOI：
10.1186/2047-783x-15-8-345
复制
发表时间：
2010-08-20
影响因子：
4.2
通讯作者：
Stockmann M
中科院分区：
文献类型：
--
作者：
Niehues SM;Unger JK;Malinowski M;Neymeyer J;Hamm B;Stockmann M
定期对肝脏进行体积评估，结果在术前和术中确定的体积之间存在差异。然而，造成这种差异的主要因素仍然不清楚。本研究的目的是在猪的动物模型上系统地确定活体CT容积法和体外容积法的差异。对11头猪进行了研究。在手术切除全肝后进行肝脏密度评估、CT体积测量和水置换体积测量。在该模型中消除了已知的可能的体积确定误差，如切除或分割边界。进行回归分析，确定CT容积法与水位法之间的差异。肝密度中位数为1.07g/ml，回归分析显示CT容积测量与水置换的相关系数R2=0.985。CT容积法比水置换容量法高13%(p<；0.0001)。在这项研究中，导致体内CT容积法和体外水置换容积法之间差异的唯一相关因素似乎是肝脏的血液灌注量。在处理这些措施时，必须考虑到13%的系统差异。
Volumetric assessment of the liver regularly yields discrepant results between pre- and intraoperatively determined volumes. Nevertheless, the main factor responsible for this discrepancy remains still unclear. The aim of this study was to systematically determine the difference between in vivo CT-volumetry and ex vivo volumetry in a pig animal model. Eleven pigs were studied. Liver density assessment, CT-volumetry and water displacement volumetry was performed after surgical removal of the complete liver. Known possible errors of volume determination like resection or segmentation borders were eliminated in this model. Regression analysis was performed and differences between CT-volumetry and water displacement determined. Median liver density was 1.07 g/ml. Regression analysis showed a high correlation of r2 = 0.985 between CT-volumetry and water displacement. CTvolumetry was found to be 13% higher than water displacement volumetry (p < 0.0001). In this study the only relevant factor leading to the difference between in vivo CT-volumetry and ex vivo water displacement volumetry seems to be blood perfusion of the liver. The systematic difference of 13 percent has to be taken in account when dealing with those measures.
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影响因子：
19.7
作者：
Schroeder, T;Nadalin, S;Ruehm, SG
通讯作者：
Ruehm, SG
影响因子：
0.6
作者：
Steinmüller, T;Pascher, A;Neuhaus, P
通讯作者：
Neuhaus, P
影响因子：
6.2
作者：
Schiano, TD;Bodian, C;Min, AD
通讯作者：
Min, AD
DOI：
10.1055/s-2004-817636
发表时间：
2004-02-01
影响因子：
1.8
作者：
Frericks, BBJ;Kiene, T;Galanski, M
通讯作者：
Galanski, M
影响因子：
6.7
作者：
Mahr, A;Levegrün, S;Schlegel, W
通讯作者：
Schlegel, W