Transcriptional scaffolds for heterochromatin assembly.

Transcriptional scaffolds for heterochromatin assembly.
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DOI:
10.1016/j.cell.2009.02.004
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发表时间:
2009-02-20
期刊:
影响因子:
64.5
通讯作者:
Grewal SI
Grewal SI
中科院分区:
生物学1区
文献类型:
--
作者:
Cam HP;Chen ES;Grewal SI

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Heterochromatin is dynamically regulated during the cell cycle and in response to developmental signals. Recent findings from diverse systems suggest an extensive role for transcription in the assembly of heterochromatin, highlighting the emerging theme that transcription and noncoding RNAs can provide the initial scaffold for the formation of heterochromatin, which serves as a versatile recruiting platform for diverse factors involved in many cellular processes.
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