Cohabitation With a Known Coronavirus Disease 2019 Case Is Associated With Greater Antibody Concentration and Symptom Severity in a Community-Based Sample of Seropositive Adults.
Cohabitation With a Known Coronavirus Disease 2019 Case Is Associated With Greater Antibody Concentration and Symptom Severity in a Community-Based Sample of Seropositive Adults.
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DOI：
10.1093/ofid/ofab244
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发表时间：
2021-07
影响因子：
4.2
通讯作者：
McDade TW
中科院分区：
文献类型：
--
作者：
Schrock JM;Ryan DT;Saber R;Benbow N;Vaught LA;Reiser N;Velez MP;Hsieh R;Newcomb M;Demonbreun AR;Mustanski B;McNally EM;D'Aquila R;McDade TW
在基于社区的血清阳性成人样本（n = 1101）中，我们发现与已知的2019冠状病毒病（COVID-19）病例一起生活的血清阳性个体与未与已知的COVID-19病例一起生活的血清阳性个体相比，表现出更高的血液抗严重急性呼吸综合征冠状病毒2刺突受体结合结构域免疫球蛋白G浓度和更严重的症状。 暴露强度可能与SARS-CoV-2感染的严重程度有关。与未与已知COVID-19病例一起生活的血清阳性参与者相比，与已知COVID-19病例一起生活的血清阳性参与者的抗体浓度更高，症状严重程度更高。
In a community-based sample of seropositive adults (n = 1101), we found that seropositive individuals who lived with a known coronavirus disease 2019 (COVID-19) case exhibited higher blood anti–severe acute respiratory syndrome coronavirus 2 spike receptor-binding domain immunoglobulin G concentrations and greater symptom severity compared to seropositive individuals who did not live with a known COVID-19 case. Exposure intensity may contribute to severity of SARS-CoV-2 infection. Seropositive participants who had lived with a known COVID-19 case had higher antibody concentrations and greater symptom severity compared to seropositive participants who had not lived with a known COVID-19 case.
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影响因子：
82.9
作者：
Brodin, Petter
通讯作者：
Brodin, Petter
影响因子：
82.9
作者：
Amanat F;Stadlbauer D;Strohmeier S;Nguyen THO;Chromikova V;McMahon M;Jiang K;Arunkumar GA;Jurczyszak D;Polanco J;Bermudez-Gonzalez M;Kleiner G;Aydillo T;Miorin L;Fierer DS;Lugo LA;Kojic EM;Stoever J;Liu STH;Cunningham-Rundles C;Felgner PL;Moran T;García-Sastre A;Caplivski D;Cheng AC;Kedzierska K;Vapalahti O;Hepojoki JM;Simon V;Krammer F
通讯作者：
Krammer F
影响因子：
4.7
作者：
Van Damme W;Dahake R;van de Pas R;Vanham G;Assefa Y
通讯作者：
Assefa Y
影响因子：
3.7
作者：
McDade, Thomas W.;McNally, Elizabeth M.;Demonbreun, Alexis R.
通讯作者：
Demonbreun, Alexis R.
影响因子：
82.9
作者：
He, Xi;Lau, Eric H. Y.;Leung, Gabriel M.
通讯作者：
Leung, Gabriel M.