CISA: contig integrator for sequence assembly of bacterial genomes.
CISA: contig integrator for sequence assembly of bacterial genomes.
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DOI:
10.1371/journal.pone.0060843
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Liao YC
中科院分区:
文献类型:
--
作者:
Lin SH;Liao YC
A plethora of algorithmic assemblers have been proposed for the de novo assembly of genomes, however, no individual assembler guarantees the optimal assembly for diverse species. Optimizing various parameters in an assembler is often performed in order to generate the most optimal assembly. However, few efforts have been pursued to take advantage of multiple assemblies to yield an assembly of high accuracy. In this study, we employ various state-of-the-art assemblers to generate different sets of contigs for bacterial genomes. A tool, named CISA, has been developed to integrate the assemblies into a hybrid set of contigs, resulting in assemblies of superior contiguity and accuracy, compared with the assemblies generated by the state-of-the-art assemblers and the hybrid assemblies merged by existing tools. This tool is implemented in Python and requires MUMmer and BLAST+ to be installed on the local machine. The source code of CISA and examples of its use are available at http://sb.nhri.org.tw/CISA/.
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影响因子:
7
作者:
Li, Ruiqiang;Zhu, Hongmei;Wang, Jun
通讯作者:
Wang, Jun
DOI:
10.1093/bioinformatics/btr451
发表时间:
2011-10-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Darling AE;Tritt A;Eisen JA;Facciotti MT
通讯作者:
Facciotti MT
DOI:
10.1093/bioinformatics/btq366
发表时间:
2010-09-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Nijkamp J;Winterbach W;van den Broek M;Daran JM;Reinders M;de Ridder D
通讯作者:
de Ridder D
影响因子:
3
作者:
通讯作者:
--
DOI:
10.1093/bioinformatics/btq284
发表时间:
2010-08-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Kislyuk AO;Katz LS;Agrawal S;Hagen MS;Conley AB;Jayaraman P;Nelakuditi V;Humphrey JC;Sammons SA;Govil D;Mair RD;Tatti KM;Tondella ML;Harcourt BH;Mayer LW;Jordan IK
通讯作者:
Jordan IK