Hörschwellenbestimmungen bei Kindern mittels früher akustisch evozierter Potenziale
Hörschwellenbestimmungen bei Kindern mittels früher akustisch evozierter Potenziale
复制标题
使用早期声诱发电位确定儿童听阈
作者：
Knaus V;Mühler R;Verhey JL
背景在儿科诊断中成功应用听觉脑干反应 (ABR) 的基本前提是确保高质量的测量。这通常通过残余噪声来量化。关键因素是自发脑电图（EEG）的平均数量和幅度。这是第一项量化不同形式镇静（麻醉、水合氯醛或褪黑素镇静、自然睡眠）对儿童个体脑电图幅度影响的研究。材料和方法对 80 名 1 个月至 6 岁儿童的 ABR 测量结果进行回顾性分析。根据平均数和残余噪声计算个体平均脑电图振幅。以镇静类型为因素对结果进行统计分析。根据平均脑电图振幅，估计了 35nV 残余噪声水平的理论记录时间。结果平均而言，清醒儿童的自发脑电图活动比自然睡眠儿童大 2.5 倍，比镇静儿童大 4 倍以上。尽管插管麻醉时的脑电图振幅小于其他三种镇静状态，但这种差异并不显着。清醒儿童35nV残余噪声的理论测量时间比镇静儿童长10倍。结论清醒儿童和镇静儿童自发脑电活动差异较大，提示镇静儿童应根据ABR估计听力阈值。只有在极少数情况下，才能从清醒儿童的 ABR 中获得可靠的听力阈值估计。由于不同类型的镇静剂不会显着影响测量时间，因此可以仅根据年龄和医学指征进行选择。
BackgroundA fundamental prerequisite for successful application of auditory brainstem responses (ABR) in paedaudiological diagnostics is to ensure a high quality of the measurement. This is commonly quantified by means of the residual noise. Key factors are the averaging number and the magnitude of spontaneous electroencephalogram (EEG). This is the first study to quantify the influence of different forms of sedation (anaesthesia, sedation with chloral hydrate or melatonin, natural sleep) on the individual EEG magnitude in children.Materials and methodsABR measurements of 80 children aged between 1 month and 6 years were analysed retrospectively. Individual mean EEG amplitude was calculated from the averaging number and the residual noise. The results were analysed statistically with the type of sedation as a factor. From the mean EEG amplitudes, a theoretical recording time for a residual noise level of 35 nV was estimated.ResultsThe spontaneous EEG activity is, on average, 2.5-times larger in awake children than in naturally sleeping children and more than 4‑times larger than in sedated children. Although the EEG amplitude in intubation anaesthesia was smaller than with the other three types of sedation, this difference was not significant. The theoretical measurement time for 35 nV of residual noise was 10-times larger in awake than in sedated children.ConclusionThe large difference in spontaneous EEG activity between awake and sedated children indicates that sedation should be used for estimation of hearing thresholds on the basis of ABR. Only in rare cases is a reliable estimate of hearing thresholds likely to be obtained from ABR in awake children. Since different types of sedation do not influence the measurement time significantly, selection can be made solely on the basis of age and medical indication.
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褪黑激素对儿童听觉脑干反应（ABR）测试的功效研究。
DOI：
10.1016/j.anorl.2017.03.006
发表时间：
2017
期刊：
European annals of otorhinolaryngology, head and neck diseases
影响因子：
--
作者：
L. Casteil;A. Viquesnel;V. Favier;N. Guignard;C. Blanchet;M. Mondain
通讯作者：
M. Mondain
Empfehlungen der AGERA zum Einsatz objektiver Hörprüfmethoden im Rahmen der pädaudiologischen Konfirmationsdiagnostik (Follow-up) nach nicht bestandenem Neugeborenen-Hörscreening
影响因子：
0.9
作者：
S. Hoth;T. Janssen;R. Mühler;M. Walger;T. Wiesner
通讯作者：
T. Wiesner
影响因子：
2.4
作者：
DON, M;ELBERLING, C
通讯作者：
ELBERLING, C
Akustisch evozierte Potenziale (AEP)
影响因子：
2.2
作者：
M. Walger;S. Hoth;R. Mühler
通讯作者：
R. Mühler
Hörschwellenbestimmungen mittels 听觉稳态响应
影响因子：
0.9
作者：
R. Mühler;T. Rahne
通讯作者：
T. Rahne