Disparities in the burden, outcomes, and care of chronic kidney disease.
Disparities in the burden, outcomes, and care of chronic kidney disease.
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DOI：
10.1097/01.mnh.0000444822.25991.f6
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发表时间：
2014-05
影响因子：
3.2
通讯作者：
Boulware LE
中科院分区：
文献类型：
--
作者：
Crews DC;Liu Y;Boulware LE
慢性肾脏疾病（CKD）的种族/民族和社会经济差异已经记录了几十年，但在减轻这些差异方面进展甚微。最近的几项研究为这些差异的根本原因提供了新的见解，指出了未来有必要进行研究的领域，并确定了政策和临床实践变革的机会。最近发表的证据表明，CKD患病率存在地理差异，并因种族而异。与白人相比，少数种族/民族群体的CKD进展更快，可能在很大程度上（但不是完全）由遗传因素解释。透析患者的结果存在明显的社会经济差异，并因种族、居住地和治疗设施而异。获得活体肾脏捐赠的差异可能主要是由捐赠者的社会经济地位而不是接受者因素驱动的。最近的研究强调了消除CKD差异的机会，包括努力将资源引导到差异最普遍的地区和人群，努力了解如何最好地利用遗传因素对差异的贡献的新信息，并继续努力确定可改变的环境，社会和行为因素，以便在高危人群中进行有针对性的干预。
Racial/ethnic and socioeconomic disparities in chronic kidney disease (CKD) have been documented for decades, yet little progress has been made in mitigating them. Several recent studies offer new insights into the root causes of these disparities, point to areas where future research is warranted and identify opportunities for changes in policy and clinical practice. Recently published evidence suggests that geographic disparities in CKD prevalence exist and vary by race. CKD progression is more rapid for racial/ethnic minority groups as compared to whites and may be largely, but not completely, explained by genetic factors. Stark socioeconomic disparities in outcomes for dialysis patients exist, and vary by race, place of residence and treatment facility. Disparities in access to living kidney donation may be driven primarily by the socioeconomic status of the donor as opposed to recipient factors. Recent studies highlight opportunities to eliminate disparities in CKD, including efforts to direct resources to areas and populations where disparities are most prevalent, efforts to understand how to best use emerging information on the contribution of genetic factors to disparities, and continued work to identify modifiable environmental, social, and behavioral factors for targeted interventions among high-risk populations.
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DOI：
10.1053/j.ajkd.2012.05.010
发表时间：
2012-11
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Crews DC;McClellan WM;Shoham DA;Gao L;Warnock DG;Judd S;Muntner P;Miller ER;Powe NR
通讯作者：
Powe NR
影响因子：
3.3
作者：
Nicholas, Susanne B.;Kalantar-Zadeh, Kamyar;Norris, Keith C.
通讯作者：
Norris, Keith C.
影响因子：
14.6
作者：
Gao, Song;Manns, Braden J.;Hemmelgarn, Brenda R.
通讯作者：
Hemmelgarn, Brenda R.
影响因子：
13.6
作者：
Gill, Jagbir;Dong, James;Gill, John
通讯作者：
Gill, John
影响因子：
120.7
作者：
Gutierrez, Orlando M.;Khodneva, Yulia A.;Muntner, Paul;Rizk, Dana V.;McClellan, William M.;Cushman, Mary;Warnock, David G.;Safford, Monika M.
通讯作者：
Safford, Monika M.