Modeling of an Optimized Electrostimulative Hip Revision System Under Consideration of Uncertainty in the Conductivity of Bone Tissue
Modeling of an Optimized Electrostimulative Hip Revision System Under Consideration of Uncertainty in the Conductivity of Bone Tissue
复制标题
考虑骨组织电导率不确定性的优化电刺激髋关节翻修系统建模
DOI:
10.1109/jbhi.2015.2423705
复制
发表时间:
2015
影响因子:
7.7
通讯作者:
van Rienen U
中科院分区:
文献类型:
--
作者:
Schmidt C;Zimmermann U;van Rienen U
Since several years, the number of total hip arthroplasty revision surgeries is substantially growing. One of the main reasons for this procedure to become necessary is the loosening or damage of the prothesis, which is facilitated by bone necrosis at the implant-bone interface. Electrostimulation is one promising technique, which can accelerate the growth of bone cells and, therefore, enhance the anchorage of the implant to the bone. We present computational models of an electrostimulative total hip revision system to enhance bone regeneration. In this study, the influence of uncertainty in the conductivity of bone tissue on the electric field strength and the beneficial stimulation volume for an optimized electrode geometry and arrangement is investigated. The generalized polynomial chaos technique is used to quantify the uncertainty in the stimulation volumes with respect to the uncertain conductivity of cancellous bone, bone marrow, and bone substitute, which is used to fill defective areas. The results suggest that the overall beneficial stimulation areas are only slightly sensitive to the uncertainty in conductivity of bone tissue. However, in the proximity of tissue boundaries, larger uncertainties, especially in the transition between beneficial and understimulation areas, can be expected.
登录
查看更多内容
影响因子:
1.9
作者:
G. Schmid;G. Neubauer;U. Illievich;F. Alesch
通讯作者:
F. Alesch
DOI:
10.1109/embc.2014.6943718
发表时间:
2014
期刊:
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
影响因子:
--
作者:
Schmidt;Zimmermann;van Rienen
通讯作者:
van Rienen
DOI:
10.1002/jbm.10015
发表时间:
2002-03-05
期刊:
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
影响因子:
--
作者:
Supronowicz, PR;Ajayan, PM;Bizios, R
通讯作者:
Bizios, R
影响因子:
2.1
作者:
U. Zimmermann;U. van Rienen
通讯作者:
U. van Rienen
DOI:
10.1109/ner.2013.6696159
发表时间:
1948
期刊:
2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)
影响因子:
--
作者:
Schmidt;van Rienen
通讯作者:
van Rienen