Evolution of fatty acid taste in drosophilids.
Evolution of fatty acid taste in drosophilids.
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DOI:
10.1016/j.celrep.2023.113297
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发表时间:
2023-10-31
期刊:
影响因子:
8.8
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中科院分区:
文献类型:
--
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Comparative studies of related but ecologically distinct species can reveal how the nervous system evolves to drive behaviors that are particularly suited to certain environments. Drosophila melanogaster is a generalist that feeds and oviposits on most overripe fruits. A sibling species, D. sechellia, is an obligate specialist of Morinda citrifolia (noni) fruit, which is rich in fatty acids (FAs). To understand evolution of noni taste preference, we characterized behavioral and cellular responses to noni-associated FAs in three related drosophilids. We find that mixtures of sugar and noni FAs evoke strong aversion in the generalist species but not in D. sechellia. Surveys of taste sensory responses reveal noni FA- and species-specific differences in at least two mechanisms—bitter neuron activation and sweet neuron inhibition–that correlate with shifts in noni preference. Chemoreceptor mutant analysis in D. melanogaster predicts that multiple genetic changes account for evolution of gustatory preference in D. sechellia. Dey et al. characterize evolution of noni acid taste in drosophilids, identifying fatty acid- and species-specific differences in sweet- and bitter-sensing circuits that correlate with differences in feeding preference for noni acids between noni host-specialist and generalist species.
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影响因子:
16.6
作者:
alvarez-Ocana, Raquel;Shahandeh, Michael P. P.;Ray, Vijayaditya;Auer, Thomas O. O.;Gompel, Nicolas;Benton, Richard
通讯作者:
Benton, Richard
影响因子:
7.7
作者:
Dweck HK;Talross GJ;Wang W;Carlson JR
通讯作者:
Carlson JR
影响因子:
7.7
作者:
Ahn JE;Chen Y;Amrein H
通讯作者:
Amrein H
影响因子:
7.7
作者:
Brown EB;Shah KD;Palermo J;Dey M;Dahanukar A;Keene AC
通讯作者:
Keene AC
影响因子:
8.8
作者:
Chen YD;Dahanukar A
通讯作者:
Dahanukar A