Rapid haplotype inference for nuclear families.
Rapid haplotype inference for nuclear families.
复制标题
DOI:
10.1186/gb-2010-11-10-r108
复制
发表时间:
2010
期刊:
影响因子:
12.3
通讯作者:
Gifford DK
中科院分区:
文献类型:
--
作者:
Williams AL;Housman DE;Rinard MC;Gifford DK
Hapi is a new dynamic programming algorithm that ignores uninformative states and state transitions in order to efficiently compute minimum-recombinant and maximum likelihood haplotypes. When applied to a dataset containing 103 families, Hapi performs 3.8 and 320 times faster than state-of-the-art algorithms. Because Hapi infers both minimum-recombinant and maximum likelihood haplotypes and applies to related individuals, the haplotypes it infers are highly accurate over extended genomic distances.
登录
查看更多内容
影响因子:
7
作者:
Lin, S;Chakravarti, A;Cutler, DJ
通讯作者:
Cutler, DJ
影响因子:
2.1
作者:
Andres, Aida M.;Clark, Andrew G.;Hixson, James E.
通讯作者:
Hixson, James E.
DOI:
10.1073/pnas.84.8.2363
发表时间:
1987-04-01
影响因子:
11.1
作者:
LANDER, ES;GREEN, P
通讯作者:
GREEN, P
影响因子:
9.8
作者:
O'Connell, JR;Weeks, DE
通讯作者:
Weeks, DE
影响因子:
30.8
作者:
Abecasis, GR;Cherny, SS;Cardon, LR
通讯作者:
Cardon, LR