[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.

[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.
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[18F]-多巴正电子发射断层扫描成像在早期非帕金青少年帕金森病中的应用。

DOI:
10.1002/mds.10133
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发表时间:
2002
期刊:
Movement disorders : official journal of the Movement Disorder Society
影响因子:
--
通讯作者:
Stoessl,AJon
Stoessl,AJon
中科院分区:
--
文献类型:
--
作者:
Pal,PramodK;Leung,Joanne;Hedrich,Katya;Samii,Ali;Lieberman,Abraham;Nausieda,PaulA;Calne,DonaldB;Breakefield,XandraO;Klein,Christine;Stoessl,AJon

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正电子发射断层扫描(PET)在青少年帕金森病(JP)中的应用报道很少。我们报告了一名14岁JP患者的18f - 6氟- L -多巴(FD) PET检查结果,该患者伴有非典型特征,病程长达5年。这是迄今为止最年轻的研究对象。纹状体FD摄取有严重的不对称减少,壳核的背侧梯度与成人发病的特发性帕金森病相似。该患者的广泛DNA分析未显示帕金基因突变。©2002运动障碍学会
There are few reports of positron emission tomography (PET) in juvenile parkinsonism (JP). We report on the results of18F‐6‐fluoro‐L‐dopa (FD) PET in a 14‐year‐old patient with JP of 5 years duration associated with atypical features. This is the youngest subject to be investigated to date. There was a severe asymmetric reduction in striatal FD uptake, with a rostrocaudal gradient in the putamen similar to that seen in adult‐onset idiopathic parkinsonism. Extensive DNA analysis in this patient did not show mutations in the parkin gene. © 2002 Movement Disorder Society
DOI: 10.1007/s13139-012-0182-4
发表时间: 2013-03-01
影响因子: 1.3
作者:
Jin, Soyoung;Oh, Minyoung;Kim, Jae Seung
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DOI: 10.1001/archneur.57.2.205
发表时间: 2000
影响因子: --
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