Two-voxel localization sequence for in vivo two-dimensional homonuclear correlation spectroscopy.

Two-voxel localization sequence for in vivo two-dimensional homonuclear correlation spectroscopy.
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用于体内二维同核相关光谱的两体素定位序列。

DOI:
10.1006/jmre.2000.2280
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发表时间:
2001
影响因子:
2.2
通讯作者:
B. Gillet
B. Gillet
中科院分区:
化学3区
文献类型:
--
作者:
Florence Delmas;F. Delmas;J. Beloeil;B. Sanden;Klaas Nicolay;B. Gillet

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与单体素采集相比,局部2D 1H MR相关光谱和Hadamard编码的结合允许同时采集多个感兴趣的体积,而不会增加实验持续时间。在本研究中,在20至40分钟内同时获得了位于大鼠大脑每个半球的两个体素的二维相关光谱。体素间距离为体素大小的20%就足以限制空间污染。以下脑代谢物具有可检测到的串音:n -乙酰天冬氨酸、谷氨酸/谷氨酰胺池、天冬氨酸、磷酸乙醇胺、葡萄糖、谷胱甘肽、牛磺酸、肌醇、乳酸、苏氨酸、γ -氨基丁酸和丙氨酸。大多数代谢物的测量没有受到其他共振的污染。
The combination of localized 2D 1H MR correlation spectroscopy and Hadamard encoding allows the simultaneous acquisition of multiple volumes of interest without an increase in the experimental duration, compared to single-voxel acquisition. In the present study, 2D correlation spectra were acquired simultaneously within 20 to 40 min in two voxels located in each hemisphere of the rat brain. An intervoxel distance of 20% of the voxel size was sufficient to limit spatial contamination. The following cerebral metabolites gave detectable crosspeaks: N-acetylaspartate, the glutamate/glutamine pool, aspartate, phosphoethanolamine, glucose, glutathione, taurine, myo-inositols, lactate, threonine, gamma-aminobutyric acid, and alanine. Most of the metabolites were measured without contamination of other resonances.
DOI: 10.1006/jmre.1999.1895
发表时间: 1999-11-01
影响因子: 2.2
作者:
Pfeuffer, J;Tkác, I;Gruetter, R
通讯作者: Gruetter, R