Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis.
Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis.
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DOI：
10.1016/j.abb.2011.02.019
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发表时间：
2011-06-15
影响因子：
3.9
通讯作者：
Cox D
中科院分区：
文献类型：
--
作者：
Park H;Ishihara D;Cox D
Macrophages display a large variety of surface receptors that are critical for their normal cellular functions in host defense, including finding sites of infection (chemotaxis) and removing foreign particles (phagocytosis). However, inappropriate regulation of these processes can lead to human diseases. Many of these receptors utilize tyrosine phosphorylation cascades to initiate and terminate signals leading to cell migration and clearance of infection. Actin remodeling dominates these processes and many regulators have been identified. This review focuses on how tyrosine kinases and phosphatases regulate actin dynamics leading to macrophage chemotaxis and phagocytosis.
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影响因子：
3.5
作者：
Baruzzi, Anna;Iacobucci, Ilaria;Berton, Giorgio
通讯作者：
Berton, Giorgio
DOI：
10.1084/jem.20030976
发表时间：
2004-01-05
期刊：
The Journal of experimental medicine
影响因子：
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作者：
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通讯作者：
Siminovitch KA
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Swanson JA
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作者：
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通讯作者：
Kaibuchi, K
影响因子：
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作者：
Al-Haddad, AH;Shonn, MA;Kuznetsov, SA
通讯作者：
Kuznetsov, SA