Genome-wide association studies provide insights into the genetic determination of fruit traits of pear.
Genome-wide association studies provide insights into the genetic determination of fruit traits of pear.
复制标题
全基因组关联研究为梨果实性状的遗传决定提供了见解
DOI：
10.1038/s41467-021-21378-y
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发表时间：
2021-02-18
影响因子：
16.6
通讯作者：
Wu J
中科院分区：
文献类型：
--
作者：
Zhang MY;Xue C;Hu H;Li J;Xue Y;Wang R;Fan J;Zou C;Tao S;Qin M;Bai B;Li X;Gu C;Wu S;Chen X;Yang G;Liu Y;Sun M;Fei Z;Zhang S;Wu J
梨是世界上主要的果树作物，但其育种是一个非常耗时的过程。为了促进分子育种和基因鉴定，我们在这里进行了全基因组关联研究（GWAS）的11个水果性状。我们确定了37个基因座与8个果实品质性状和5个基因座与3个果实物候性状。选择扫描表明，在育种改良过程中，核果细胞含量、有机酸和糖含量等性状可能受到了连续选择。在GWAS中鉴定的一个候选基因PbrSTONE已被功能验证参与梨最重要的果实品质性状之一石细胞形成的调控。我们的研究为复杂的水果相关生物学提供了见解，并通过GWAS确定了控制梨重要性状的基因，这扩展了遗传资源和促进多年生树木分子育种的基础。
Pear is a major fruit tree crop distributed worldwide, yet its breeding is a very time-consuming process. To facilitate molecular breeding and gene identification, here we have performed genome-wide association studies (GWAS) on eleven fruit traits. We identify 37 loci associated with eight fruit quality traits and five loci associated with three fruit phenological traits. Scans for selective sweeps indicate that traits including fruit stone cell content, organic acid and sugar contents might have been under continuous selection during breeding improvement. One candidate gene,PbrSTONE, identified in GWAS, has been functionally verified to be involved in the regulation of stone cell formation, one of the most important fruit quality traits in pear. Our study provides insights into the complex fruit related biology and identifies genes controlling important traits in pear through GWAS, which extends the genetic resources and basis for facilitating molecular breeding in perennial trees.
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影响因子：
3
作者：
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通讯作者：
Horvath S
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