Behavioral phenotype of fragile X syndrome in adolescence and adulthood.
Behavioral phenotype of fragile X syndrome in adolescence and adulthood.
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DOI：
10.1352/1944-7558-117.1.1
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发表时间：
2012-01
期刊：
影响因子：
--
通讯作者：
Greenberg JS
中科院分区：
文献类型：
--
作者：
Smith LE;Barker ET;Seltzer MM;Abbeduto L;Greenberg JS
本研究探讨了脆性X染色体综合征个体在青春期和成年期的行为特征。同时患有脆性X综合征和自闭症的个体（n = 30）与(a)被诊断为脆性X综合征的个体（但不是自闭症；n = 106）和(b)被诊断为自闭症的个体（但不是脆性X综合征；n = 135）在自闭症症状、适应功能、行为问题和心理症状的测量上进行了比较。结果表明，脆性X综合征和自闭症双重诊断的个体比仅患有脆性X综合征的个体表现出更大的沟通和社会互惠障碍。与任何一个对照组相比，双重诊断组的个体也表现出更高水平的重复性和挑战性行为，这表明那些同时被诊断为脆性X综合征和自闭症的人具有独特的脆弱性。
The present study explored the behavioral profile of individuals with fragile X syndrome during adolescence and adulthood. Individuals with both fragile X syndrome and autism (n = 30) were compared with (a) individuals diagnosed with fragile X syndrome (but not autism; n = 106) and (b) individuals diagnosed with autism (but not fragile X syndrome; n = 135) on measures of autism symptoms, adaptive functioning, behavior problems, and psychological symptoms. Results indicated that individuals dually diagnosed with fragile X syndrome and autism displayed greater communication and social reciprocity impairments than individuals with fragile X syndrome only. Individuals in the dually diagnosed group also exhibited higher levels of repetitive and challenging behaviors than either comparison group, suggesting a unique profile of vulnerability for those diagnosed with both fragile X syndrome and autism.
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影响因子：
3.9
作者：
Esbensen, Anna J.;Seltzer, Marsha Mailick;Bodfish, James W.
通讯作者：
Bodfish, James W.
DOI：
10.1352/1944-7558-116.1.16
发表时间：
2011-01-01
影响因子：
2.1
作者：
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通讯作者：
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DOI：
10.1111/j.1365-2788.2006.00803.x
发表时间：
2006-07-01
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
4.1
作者：
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