Implications of temperature variation for malaria parasite development across Africa.

Implications of temperature variation for malaria parasite development across Africa.
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DOI:
10.1038/srep01300
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发表时间:
2013
期刊:
影响因子:
4.6
通讯作者:
Thomas, M. B.
Thomas, M. B.
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Blanford, J. I.;Blanford, S.;Crane, R. G.;Mann, M. E.;Paaijmans, K. P.;Schreiber, K. V.;Thomas, M. B.

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温度是疟疾传播的一个重要决定因素。最近的研究表明,蚊子和寄生虫的生物学不仅受到平均温度的影响,而且还受到每日温度变化程度的影响。在这里,我们研究如何寄生虫的蚊子内的发展(外部孵化期)预计会随着时间和空间的变化,这取决于在肯尼亚和整个非洲的昼夜温度范围和基线平均温度。我们的研究结果表明,在凉爽的条件下,典型的方法,仅使用平均月温度来表征传播环境会低估寄生虫的发展。相反,在较温暖的条件下,使用平均温度将高估发展。在室外和室内温度下,质量上类似的模式都成立。这些发现对确定疟疾风险具有重要意义。此外,了解每日温度动态的影响,可以提供新的见解外温生态现在和未来的气候变化。
Temperature is an important determinant of malaria transmission. Recent work has shown that mosquito and parasite biology are influenced not only by average temperature, but also by the extent of the daily temperature variation. Here we examine how parasite development within the mosquito (Extrinsic Incubation Period) is expected to vary over time and space depending on the diurnal temperature range and baseline mean temperature in Kenya and across Africa. Our results show that under cool conditions, the typical approach of using mean monthly temperatures alone to characterize the transmission environment will underestimate parasite development. In contrast, under warmer conditions, the use of mean temperatures will overestimate development. Qualitatively similar patterns hold using both outdoor and indoor temperatures. These findings have important implications for defining malaria risk. Furthermore, understanding the influence of daily temperature dynamics could provide new insights into ectotherm ecology both now and in response to future climate change.
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