Treatment decision-making in acute myeloid leukemia: a qualitative study of older adults and community oncologists.
Treatment decision-making in acute myeloid leukemia: a qualitative study of older adults and community oncologists.
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DOI：
10.1080/10428194.2020.1832662
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发表时间：
2021-03
影响因子：
2.6
通讯作者：
Klepin HD
中科院分区：
文献类型：
--
作者：
Loh KP;Abdallah M;Kadambi S;Wells M;Kumar AJ;Mendler JH;Liesveld JL;Wittink M;O'Dwyer K;Becker MW;McHugh C;Stock W;Majhail NS;Wildes TM;Duberstein P;Mohile SG;Klepin HD
对影响老年AML患者治疗决策的患者、医生和组织的特征知之甚少。我们对社区肿瘤学家和老年AML患者进行了定性访谈，以了解影响他们治疗决策的因素。通过目的性抽样进行招募，并持续至达到理论饱和，最终纳入15名患者和15名肿瘤学家。参与者的回答使用定向内容分析进行分析。肿瘤学家和患者在决定治疗时考虑了合并症、功能状态、情绪健康、认知和社会因素;大多数肿瘤学家使用临床完形来评估这些因素。67%的患者认为治疗是他们唯一的选择，他们没有选择。总之，治疗决策是复杂的，受患者相关因素的影响。这些因素可以作为老年评估的一部分进行评估，这可以帮助肿瘤学家更好地确定健康状况并指导治疗决策。
Little is known about the characteristics of patients, physicians, and organizations that influence treatment decisions in older patients with AML. We conducted qualitative interviews with community oncologists and older patients with AML to elicit factors that influence their treatment decision-making. Recruitment was done via purposive sampling and continued until theoretical saturation was reached, resulting in the inclusion of 15 patients and 15 oncologists. Participants’ responses were analyzed using directed content analysis. Oncologists and patients considered comorbidities, functional status, emotional health, cognition, and social factors when deciding treatment; most oncologists evaluated these using clinical gestalt. Sixty-seven percent of patients perceived that treatment was their only option and that they had not been offered a choice. In conclusion, treatment decision-making is complex and influenced by patient-related factors. These factors can be assessed as part of a geriatric assessment which can help oncologists better determine fitness and guide treatment decision-making.
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影响因子：
4.7
作者：
Abdallah M;Xie Z;Ready A;Manogna D;Mendler JH;Loh KP
通讯作者：
Loh KP
影响因子：
3.2
作者：
Hsieh, HF;Shannon, SE
通讯作者：
Shannon, SE
影响因子：
2.8
作者：
Bergkvist, Karin;Larsen, Joacim;Svahn, Britt-Marie
通讯作者：
Svahn, Britt-Marie
影响因子：
10.1
作者：
Deschler, Barbara;Ihorst, Gabriele;Luebbert, Michael
通讯作者：
Luebbert, Michael
影响因子：
6.2
作者：
Kantarjian, H;O'Brien, S;Estey, E
通讯作者：
Estey, E