Changes in brain activation patterns according to cross-training effect in serial reaction time task: An functional MRI study.
Changes in brain activation patterns according to cross-training effect in serial reaction time task: An functional MRI study.
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DOI：
10.3969/j.issn.1673-5374.2013.07.008
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发表时间：
2013-03-05
影响因子：
6.1
通讯作者：
Park JW
中科院分区：
文献类型：
--
作者：
Kwon YH;Kwon JW;Park JW
交叉训练是一种与运动学习相关的现象，其中未经训练的肢体的运动表现在对同源对侧肢体进行单侧训练后显示出力量和技能执行的改善。我们使用功能性磁共振成像来研究是否可以使用一个串行反应时间任务，根据运动顺序学习的训练肢体的未训练肢体的运动性能得到改善，以及这些技能收购是否导致大脑激活模式的变化。我们招募了20名右利手的健康受试者，他们被随机分配到训练组和对照组。训练组在连续反应时间任务中使用他们的非优势左手进行训练，每天40分钟，持续10天，为期2周。对照组不接受训练。在训练前和训练后进行了两次反应时间和百分位数的反应准确性的测量，而大脑功能MRI扫描期间使用未经训练的右手执行的系列反应时间任务。在训练组中，未训练的右手和训练的左手在训练前后的反应时间和反应准确性的百分位数都有显著变化。对照组在训练前和训练后未训练的手没有显着变化。在训练组中，与运动功能相关的皮质区的激活体积（即，初级运动皮层、运动前区、后顶叶皮层）显示出逐渐减少，并且在使用未经训练的右手执行系列反应时间任务期间观察到小脑蚓部和新激活的同侧齿状核的增强的激活，伴随着交叉运动学习效应。然而，在对照组中未观察到显著变化。我们的研究结果表明，在2周的训练中，使用训练过的肢体学到的运动技能被转移到相对的同源肢体，而未经训练的肢体的运动技能获得导致大脑皮层和小脑的大脑激活模式的变化。
Cross-training is a phenomenon related to motor learning, where motor performance of the untrained limb shows improvement in strength and skill execution following unilateral training of the homologous contralateral limb. We used functional MRI to investigate whether motor performance of the untrained limb could be improved using a serial reaction time task according to motor sequential learning of the trained limb, and whether these skill acquisitions led to changes in brain activation patterns. We recruited 20 right-handed healthy subjects, who were randomly allocated into training and control groups. The training group was trained in performance of a serial reaction time task using their non-dominant left hand, 40 minutes per day, for 10 days, over a period of 2 weeks. The control group did not receive training. Measurements of response time and percentile of response accuracy were performed twice during pre- and post-training, while brain functional MRI was scanned during performance of the serial reaction time task using the untrained right hand. In the training group, prominent changes in response time and percentile of response accuracy were observed in both the untrained right hand and the trained left hand between pre- and post-training. The control group showed no significant changes in the untrained hand between pre- and post-training. In the training group, the activated volume of the cortical areas related to motor function (i.e., primary motor cortex, premotor area, posterior parietal cortex) showed a gradual decrease, and enhanced cerebellar activation of the vermis and the newly activated ipsilateral dentate nucleus were observed during performance of the serial reaction time task using the untrained right hand, accompanied by the cross-motor learning effect. However, no significant changes were observed in the control group. Our findings indicate that motor skills learned over the 2-week training using the trained limb were transferred to the opposite homologous limb, and motor skill acquisition of the untrained limb led to changes in brain activation patterns in the cerebral cortex and cerebellum.
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影响因子：
4.1
作者：
Hortobágyi T;Richardson SP;Lomarev M;Shamim E;Meunier S;Russman H;Dang N;Hallett M
通讯作者：
Hallett M
影响因子：
2.5
作者：
Han, Ying;Yang, Hong;Dong, Qi
通讯作者：
Dong, Qi
影响因子：
2.7
作者：
Farthing, Jonathan P.;Borowsky, Ron;Sarty, Gordon E.
通讯作者：
Sarty, Gordon E.
DOI：
10.1249/mss.0b013e318210783c
发表时间：
2011-08-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Farthing, Jonathan P.;Krentz, Joel R.;Borowsky, Ron
通讯作者：
Borowsky, Ron
DOI：
10.1097/00005768-199701000-00015
发表时间：
1997-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Hortobagyi, T;Lambert, NJ;Hill, JP
通讯作者：
Hill, JP