Relationship between temporomandibular disorders, widespread palpation tenderness, and multiple pain conditions: a case-control study.
Relationship between temporomandibular disorders, widespread palpation tenderness, and multiple pain conditions: a case-control study.
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颞下颌疾病，广泛的触诊压痛与多种疼痛状况之间的关系：病例对照研究。
DOI：
10.1016/j.jpain.2012.07.011
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发表时间：
2012-10
期刊：
影响因子：
4
通讯作者：
Diatchenko, Luda
中科院分区：
文献类型：
--
作者：
Chen, Hong;Slade, Gary;Lim, Pei Feng;Miller, Vanessa;Maixner, William;Diatchenko, Luda
颞下颌关节紊乱病（TMD）中的多种身体疼痛状况与疼痛处理的普遍改变有关。本研究的目的是检查广泛的身体触诊压痛（WPT）的存在和多种共病疼痛条件的可能性在TMD患者和对照之间的关系。对76例伴有WPT的TMD患者、83例无WPT的TMD患者和181例非TMD患者进行了病例对照研究。研究人群还包括临床疼痛、实验性疼痛敏感性和相关心理表型。结果显示：（1）TMD患者平均报告1.7种共病疼痛状况，而对照组平均报告0.3种共病疼痛状况（p<0.001）;（2）与对照组相比，伴有WPT的TMD受试者的多种共病疼痛状况的比值比（OR）更高[OR 8.4（95% CI 3.1-22.8）TMD伴WPT vs OR 3.3（3）与无WPT的TMD受试者相比，有WPT的TMD受试者在颅区和颅外区的压力痛阈值（PPT）均降低;（4）伴有WPT的TMD患者躯体症状增多。这些研究结果表明，疼痛评估以外的口面部区域可能被证明是有价值的分类，诊断和管理的TMD患者。
The multiple bodily pain conditions in temporomandibular disorders (TMD) have been associated with generalized alterations in pain processing. The purpose of this study was to examine the relationship between the presence of widespread body palpation tenderness (WPT) and the likelihood of multiple comorbid pain conditions in TMD patients and controls. This case-control study was conducted in 76 TMD subjects with WPT, 83 TMD subjects without WPT, and 181 non-TMD matched control subjects. The study population was also characterized for clinical pain, experimental pain sensitivity, and related psychological phenotypes. Results showed that (1) TMD subjects reported an average of 1.7 comorbid pain conditions compared to 0.3 reported by the control subjects (p<0.001); (2) Compared to control subjects, the odds ratio (OR) for multiple comorbid pain conditions is higher for TMD subjects with WPT [OR 8.4 (95% CI 3.1–22.8) for TMD with WPT versus OR 3.3 (95% CI 1.3–8.4) for TMD without WPT]; (3) TMD subjects with WPT presented with reduced pressure pain thresholds (PPTs) in both cranial and extra-cranial regions compared to TMD subjects without WPT; and (4) TMD subjects with WPT reported increased somatic symptoms. These findings suggest that pain assessment outside of the orofacial region may prove valuable for the classification, diagnosis, and management of TMD patients.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
3.6
作者：
Jensen, Ole Kudsk;Nielsen, Claus Vinther;Stengaard-Pedersen, Kristian
通讯作者：
Stengaard-Pedersen, Kristian
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作者：
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通讯作者：
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作者：
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通讯作者：
Turner, Judith A
影响因子：
2
作者：
Fernandez-de-las-Penas, Cesar;Galan-del-Rio, Fernando;Svensson, Peter
通讯作者：
Svensson, Peter