Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage 1 hypertension: an open-label single-arm trial.
Effects of the DASH-JUMP dietary intervention in Japanese participants with high-normal blood pressure and stage 1 hypertension: an open-label single-arm trial.
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DOI：
10.1038/hr.2016.76
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发表时间：
2016-11
影响因子：
5.4
通讯作者：
Kobayashi, Sei
中科院分区：
文献类型：
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作者：
Kawamura, Atsuko;Kajiya, Katsuko;Kishi, Hiroko;Inagaki, Junko;Mitarai, Makoto;Oda, Hiroshi;Umemoto, Seiji;Kobayashi, Sei
美国心脏协会推荐采用DASH（Dietary Approaches to Stop Hypertension）饮食来降低血压;然而，其在日本参与者中的效果尚未得到严格研究。我们评估了DASH-Japan Ube改良饮食计划（DASH-JUMP）（一种改良的DASH饮食）对未经治疗的正常高血压或1期高血压日本参与者的心脏代谢和炎症生物标志物的影响。58名患有未经治疗的正常高血压或1期高血压的参与者（30名男性和28名女性;平均年龄54.1±8.1岁）遵循DASH-JUMP（盐8.0 g/天）2个月。干预期结束后，他们恢复正常饮食4个月。DASH-JUMP显著降低了参与者的体重指数值（基线时24.6±3.5 kg m−2 → 2个月时23.2±3.3 kg m−2，P=0.000），BP（基线时153±14/91±11 mm Hg → 2个月时130±16/80±9 mm Hg，P=0.000和6个月时139±16/85±10 mm Hg，P=0.000），空腹血糖水平（2个月时100±26 mg dl−1→94±15 mg dl−1，P=0.003）和空腹胰岛素水平（2个月时6.9±5.9 μIU ml−1→4.4±2.7 μIU ml−1，P=0.000）。参与者对DASH-JUMP饮食的平均依从性为88.5%。DASH-JUMP饮食减少了心血管风险因素，可能是预防心血管事件的有效营养策略。
The Dietary Approaches to Stop Hypertension (DASH) diet is recommended by the American Heart Association to lower blood pressure (BP); however, its effects in Japanese participants have not been rigorously studied. We assessed the effects of the DASH-Japan Ube Modified diet Program (DASH-JUMP), a modified DASH diet, on cardiometabolic and inflammatory biomarkers in Japanese participants with untreated high-normal BP or stage 1 hypertension. Fifty-eight participants (30 men and 28 women; mean age 54.1±8.1 years) with untreated high-normal BP or stage 1 hypertension followed the DASH-JUMP (salt 8.0 g per day) for 2 months. After the intervention period, they resumed their usual diets for 4 months. The DASH-JUMP significantly decreased the participants' body mass index values (24.6±3.5 kg m−2 at baseline→23.2±3.3 kg m−2 at 2 months, P=0.000), BP (153±14/91±11 mm Hg at baseline→130±16/80±9 mm Hg at 2 months, P=0.000 and 139±16/85±10 mm Hg at 6 months, P=0.000), fasting serum glucose level (100±26 mg dl−1→94±15 mg dl−1 at 2 months, P=0.003) and fasting insulin level (6.9±5.9 μIU ml−1→4.4±2.7 μIU ml−1 at 2 months, P=0.000). The mean compliance of the participants for the DASH-JUMP diet was 88.5%. The DASH-JUMP diet reduced cardiovascular risk factors and may be an effective nutritional strategy for preventing cardiovascular events.
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影响因子：
--
作者：
Cook, Nancy R.;Obarzanek, Eva;Cutler, Jeffrey A.;Buring, Julie E.;Rexrode, Kathryn M.;Kumanyika, Shiriki K.;Appel, Lawrence J.;Whelton, Paul K.
通讯作者：
Whelton, Paul K.
影响因子：
5.4
作者：
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通讯作者：
Ueshima, Hirotsugu
影响因子：
16.2
作者：
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通讯作者：
Svetkey, LP
影响因子：
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作者：
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通讯作者：
Boutron-Ruault, MC
影响因子：
5.6
作者：
Hinderliter, Alan L.;Babyak, Michael A.;Blumenthal, James A.
通讯作者：
Blumenthal, James A.