Relationship between socioeconomic status and gastrointestinal infections in developed countries: A systematic review and meta-analysis.
Relationship between socioeconomic status and gastrointestinal infections in developed countries: A systematic review and meta-analysis.
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发达国家的社会经济地位与胃肠道感染之间的关系：系统评价和荟萃分析。
DOI：
10.1371/journal.pone.0191633
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Taylor-Robinson DC
中科院分区：
文献类型：
--
作者：
Adams NL;Rose TC;Hawker J;Violato M;O'Brien SJ;Barr B;Howard VJK;Whitehead M;Harris R;Taylor-Robinson DC
社会经济地位（SES）和健康之间的关联是有据可查的;然而，关于SES和胃肠道（GI）感染之间关系的证据有限，已发表的研究产生了相互矛盾的结果。本系统综述旨在评估SES与GI感染风险之间的相关性，并探索文献中报告的效应估计值异质性的可能来源。检索了1980年至2015年10月的MEDLINE、Scopus、Web of Science和灰色文献，以寻找报告经济合作与发展组织成员国代表性人群样本中GI感染与SES之间相关性的研究。使用收获图和荟萃回归研究异质性的潜在来源，如年龄; SES变量水平; GI感染测量;和主要传播方式。该方案已在PROSPERO上注册：CRD 42015027231。共识别出6021项研究; 102项符合纳入标准。年龄被确定为SES和GI感染风险之间的关联的唯一统计学显著的潜在影响因素。对于儿童，较低SES的GI感染风险高于较高SES的GI感染风险（RR 1.51，95% CI;1.26-1.83），但与成人无关（RR 0.79，95% CI;0.58-1.06）。在单变量分析中，与食源性病原体相比，低SES组和高SES组通过人际传播传播的病原体的风险增加显著较高，但环境病原体的风险较低。糖尿病儿童，而不是成年人，有更大的风险，胃肠道感染相比，他们的更多的同行。存在高度异质性，许多研究质量较低。需要更多高质量的研究来调查SES和GI感染风险之间的关系，未来的研究应该按年龄和病原体类型进行分层分析。进一步了解这种关系将有助于为减少儿童胃肠道疾病不平等的政策提供信息。
The association between socioeconomic status (SES) and health is well-documented; however limited evidence on the relationship between SES and gastrointestinal (GI) infections exists, with published studies producing conflicting results. This systematic review aimed to assess the association between SES and GI infection risk, and explore possible sources of heterogeneity in effect estimates reported in the literature. MEDLINE, Scopus, Web of Science and grey literature were searched from 1980 to October 2015 for studies reporting an association between GI infections and SES in a representative population sample from a member-country of the Organisation for Economic Co-operation and Development. Harvest plots and meta-regression were used to investigate potential sources of heterogeneity such as age; level of SES variable; GI infection measurement; and predominant mode of transmission. The protocol was registered on PROSPERO: CRD42015027231. In total, 6021 studies were identified; 102 met the inclusion criteria. Age was identified as the only statistically significant potential effect modifier of the association between SES and GI infection risk. For children, GI infection risk was higher for those of lower SES versus high (RR 1.51, 95% CI;1.26–1.83), but there was no association for adults (RR 0.79, 95% CI;0.58–1.06). In univariate analysis, the increased risk comparing low and high SES groups was significantly higher for pathogens spread by person-to-person transmission, but lower for environmental pathogens, as compared to foodborne pathogens. Disadvantaged children, but not adults, have greater risk of GI infection compared to their more advantaged counterparts. There was high heterogeneity and many studies were of low quality. More high quality studies are needed to investigate the association between SES and GI infection risk, and future research should stratify analyses by age and pathogen type. Gaining further insight into this relationship will help inform policies to reduce inequalities in GI illness in children.
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影响因子：
11.8
作者：
Coker AO;Isokpehi RD;Thomas BN;Amisu KO;Obi CL
通讯作者：
Obi CL
DOI：
10.1053/j.spid.2005.12.008
发表时间：
2005-04-01
期刊：
Seminars in pediatric infectious diseases
影响因子：
--
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
van Duynhoven, YTHF
影响因子：
3.7
作者：
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通讯作者：
Shekelle, Paul G.
影响因子：
3.6
作者：
Jackson, Rebecca;Smith, Daniel;Vugia, Duc
通讯作者：
Vugia, Duc