Effects of genetic information on memory for severity of depressive symptoms.
Effects of genetic information on memory for severity of depressive symptoms.
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DOI：
10.1371/journal.pone.0239714
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发表时间：
2020
期刊：
影响因子：
3.7
通讯作者：
Lebowitz M
中科院分区：
文献类型：
--
作者：
Ahn WK;Bitran A;Lebowitz M
公众越来越意识到基因在导致抑郁症中的作用。最近的研究已经开始揭示了解一个人对疾病的遗传易感性的意外负面后果。因为人们倾向于相信基因决定一个人的身份，所以拥有与疾病相关的基因可能会被误解为等同于患有该疾病。因此，得知一个人在遗传上易患抑郁症可能会使人们将轻度抑郁误认为是更严重的抑郁。三个实验的参与者阅读了关于表现出轻度抑郁症状的角色的目标小插图，同时对角色对抑郁症的遗传易感性的描述进行了实验操纵。然后，参与者阅读一段箔片小插图，描述一个患有更严重抑郁症状的角色。之后，得知目标角色在遗传上易患抑郁症的参与者相对更有可能将目标症状误认为是严重的，而实际上这些症状是轻微的。这种结果模式是在非专业人士（实验 1 和 2）和硕士水平（但不是博士水平）的心理健康临床医生（实验 3）中获得的。鉴于抑郁症的诊断主要基于一个人对抑郁症状的记忆，目前的研究结果表明，有关抑郁症的遗传信息可能会导致抑郁症的过度诊断。
The general public is increasingly aware of the role of genes in causing depression. Recent studies have begun uncovering unintended negative consequences of learning about a person’s genetic susceptibility to disorders. Because people tend to believe that genes determine one’s identity, having genes related to a disorder can be misinterpreted as equivalent to having the disorder. Consequently, learning that a person is genetically predisposed to depression can make people misremember mild depression as more severe. Participants across three experiments read a target vignette about a character displaying mild depressive symptoms, while descriptions of the character’s genetic susceptibility to depression were experimentally manipulated. Participants then read a foil vignette describing a character with more severe depressive symptoms. Afterwards, participants who had learned that the target character was genetically predisposed to depression were comparatively more likely to misremember the target symptoms as being severe, when in fact they were mild. This pattern of results was obtained among both laypeople (Experiments 1 and 2) and practicing master’s-level, but not doctoral-level, mental health clinicians (Experiment 3). Given that depression is diagnosed primarily based on a person’s memory of depressive symptoms, the current findings suggest that genetic information about depression may lead to over-diagnosis of depression.
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影响因子：
6.7
作者：
Schomerus, G.;Schwahn, C.;Angermeyer, M. C.
通讯作者：
Angermeyer, M. C.
“像其他任何疾病”？公众对精神分裂症，抑郁和酒精依赖的反应变化了十年。
DOI：
10.1176/appi.ajp.2010.09121743
发表时间：
2010-11
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Pescosolido BA;Martin JK;Long JS;Medina TR;Phelan JC;Link BG
通讯作者：
Link BG
影响因子：
5.9
作者：
Lebowitz MS;Ahn WK
通讯作者：
Ahn WK
DOI：
10.1073/pnas.1414058111
发表时间：
2014-12-16
影响因子：
11.1
作者：
Lebowitz, Matthew S.;Ahn, Woo-kyoung
通讯作者：
Ahn, Woo-kyoung
影响因子：
7.6
作者：
BODENHAUSEN, GV;LICHTENSTEIN, M
通讯作者：
LICHTENSTEIN, M