A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis.
A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis.
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DOI：
10.3390/cancers13092025
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发表时间：
2021-04-22
期刊：
影响因子：
5.2
通讯作者：
Przybyłowicz KE
中科院分区：
文献类型：
--
作者：
Sawicki T;Ruszkowska M;Danielewicz A;Niedźwiedzka E;Arłukowicz T;Przybyłowicz KE
根据现有资料，结直肠癌（CRC）是最常见的恶性肿瘤之一。根据位置，癌症类型或性别，它在世界上的发病率排名第2至第4位。CRC的发病率和死亡率逐年上升。许多因素可能导致这种疾病的发生，包括遗传和环境因素。考虑到所有方面，我们努力系统化现有文献数据，包括流行病学、危险因素、症状类型和性质、发展阶段、现有和未来的结直肠癌诊断。这篇综述文章包含了对结直肠癌遗传和环境危险因素的简要考虑。与结直肠癌相关的已知风险因素包括家族和遗传因素以及生活方式相关和生态因素。生活方式因素是重要的，因为有可能提高我们对疾病的认识。缺乏身体活动、肥胖、吸烟和饮酒也可以通过治疗干预来解决。我们还努力将关于流行病学、诊断、症状类型和性质以及疾病阶段的现有文献和数据系统化。对结直肠癌的进一步研究和全球取得的进展对于通过基于人群的预防措施控制疾病负担的未来战略至关重要。
According to the available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on the location, type of cancer or gender, it is ranked 2nd to 4th in terms of incidence in the world. CRC, year by year, shows an increasing tendency in terms of both morbidity and deaths. Many factors may be responsible for the development of this disease, including genetic and environmental factors. Considering all the aspects, we made efforts to systematize the available literature data in terms of epidemiology, risk factors, type and nature of symptoms, development stages, available and future diagnosis of colorectal cancer. This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity, smoking and alcohol consumption can also be addressed through therapeutic interventions. We also made efforts to systematize available literature and data on epidemiology, diagnosis, type and nature of symptoms and disease stages. Further study of colorectal cancer and progress made globally is crucial to inform future strategies in controlling the disease’s burden through population-based preventative initiatives.
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DOI：
10.1001/jama.2016.4226
发表时间：
2016-04-26
期刊：
JAMA
影响因子：
--
作者：
Chetty R;Stepner M;Abraham S;Lin S;Scuderi B;Turner N;Bergeron A;Cutler D
通讯作者：
Cutler D
影响因子：
2.5
作者：
Douaiher, Jeffrey;Ravipati, Advaitaa;Are, Chandrakanth
通讯作者：
Are, Chandrakanth
影响因子：
3.7
作者：
Chan DS;Lau R;Aune D;Vieira R;Greenwood DC;Kampman E;Norat T
通讯作者：
Norat T
影响因子：
4.3
作者：
Coppede, Fabio;Lopomo, Angela;Migliore, Lucia
通讯作者：
Migliore, Lucia
影响因子：
3.2
作者：
Ajouz H;Mukherji D;Shamseddine A
通讯作者：
Shamseddine A