The impact of paternal alcohol, tobacco, caffeine use and physical activity on offspring mental health: a systematic review and meta-analysis.
The impact of paternal alcohol, tobacco, caffeine use and physical activity on offspring mental health: a systematic review and meta-analysis.
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DOI：
10.1186/s12978-021-01266-w
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发表时间：
2021-10-26
影响因子：
3.4
通讯作者：
Sharp GC
中科院分区：
文献类型：
--
作者：
Easey KE;Sharp GC
有一些证据表明，父亲在怀孕期间和怀孕前后的健康行为可能与后代的健康结果有关。然而，怀孕期间父亲的健康行为对后代心理健康的影响尚未得到充分研究，目前仍不清楚。我们对PubMed上的文章进行了系统回顾和荟萃分析，这些文章描述了产前可能改变的父亲健康行为（吸烟、饮酒、咖啡因摄入和体育活动）与后代心理健康的关系。GRADE用于测量偏倚风险。纳入8项研究，并按父亲健康行为和后代心理健康结果进行分类。叙述性综合提供了怀孕期间父亲的健康行为与后代精神健康问题之间存在关联的证据，其中最有力的证据显示与烟草使用有关。根据分析类型分组，两项独立的荟萃分析显示，父亲在怀孕期间吸烟与后代患ADHD的几率较高相关（OR 1.42, 95% CI 1.02-1.99; HR 1.28, 95% CI 1.19-1.39）。调查父亲产前对子女心理健康影响的研究为数不多，而且这些研究的样本量有限，因此很难得出确切的结论。虽然现有的研究表明，父亲在产前吸烟和饮酒与后代较差的心理健康（特别是多动症/多动症）有关，但需要进一步调查潜在的父亲影响，使用允许更强推断的方法来确定这种关联是否存在因果关系。在线版本包含补充材料，可在10.1186/s12978-021-01266-w获得。更多的研究侧重于母亲在怀孕期间和怀孕前后的行为（如吸烟或饮酒）可能对子女健康产生的影响，而较少研究调查父亲健康行为可能发挥的作用。这篇综述收集了目前可用的研究，调查了父亲在怀孕期间饮酒、吸烟、使用咖啡因和体育活动对孩子心理健康的影响。我们展示了这一领域目前正在研究中，只发现了8项研究。然而，在已经发表的研究中，我们发现了父亲健康行为对儿童心理健康产生影响的证据。最有力的证据表明，父亲在怀孕期间吸烟对孩子的多动/多动症有负面影响。没有研究测量父亲在怀孕期间的咖啡因摄入量或身体活动。这篇综述强调了缺乏调查父亲在怀孕期间可改变的健康行为与后代心理健康之间关系的研究。尽管包括了四种不同类型的父亲健康行为，以及对任何年龄段子女心理健康的广泛定义，但只有八项研究得到了证实。这项审查表明，需要在这一领域进行进一步的研究，这可能会影响在受孕前和怀孕期间对潜在父亲的健康警告。在线版本包含补充材料，可在10.1186/s12978-021-01266-w获得。
There is some evidence that paternal health behaviours during and around pregnancy could be associated with offspring health outcomes. However, the impact that paternal health behaviours during pregnancy can have on offspring mental health is understudied and remains unclear. We conducted a systematic review and meta-analysis of articles in PubMed describing studies of potentially modifiable paternal health behaviours (tobacco smoking, alcohol consumption, caffeine consumption and physical activity) in the prenatal period in relation to offspring mental health. GRADE was used to measure risk of bias. Eight studies were included and categorized by paternal health behaviour and offspring mental health outcome investigated. The narrative synthesis provided evidence of association between paternal health behaviours around pregnancy and offspring mental health problems, with the strongest evidence shown for tobacco use. Grouped by analysis type, two separate meta-analyses showed evidence of paternal smoking during pregnancy being associated with greater odds of ADHD in offspring (OR 1.42, 95% CI 1.02–1.99; HR 1.28, 95% CI 1.19–1.39). The small number of studies that have investigated paternal prenatal effects on offspring mental health, and the limited sample sizes of those studies, makes it challenging to draw firm conclusions. Although existing studies suggest that paternal tobacco smoking and alcohol consumption in the prenatal period are associated with poorer offspring mental health, (particularly hyperactivity/ADHD), further investigation of potential paternal effects is required, using methods that allow stronger inference to determine whether associations are causal. The online version contains supplementary material available at 10.1186/s12978-021-01266-w. More research has focused on the impact mothers’ behaviours (such as smoking or alcohol use) during and around pregnancy may have on their children’s health, with less research investigating the role paternal health behaviours may play. This review captured what research was currently available that investigated the impact of paternal alcohol, tobacco, caffeine use, and physical activity during pregnancy on children’s mental health. We showed that this area is currently under researched, finding only eight studies. However, of the research that was already published we found evidence of paternal health behaviours having an impact on children’s mental health. The strongest evidence was shown for paternal smoking during pregnancy having a negative impact on children’s hyperactivity/ADHD. No studies measured paternal caffeine use or physical activity around pregnancy. This review highlights the lack of research that has investigated the association between paternal modifiable health behaviours around pregnancy and offspring mental health. Despite including four different types of paternal health behaviours and a broad definition of offspring mental health across any age, only eight studies were shown. This review suggests further research within this area is needed which may influence health warnings to potential fathers to be both before conception and during pregnancy. The online version contains supplementary material available at 10.1186/s12978-021-01266-w.
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DOI：
10.1097/ede.0b013e3181d61eeb
发表时间：
2010-05
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Lipsitch M;Tchetgen Tchetgen E;Cohen T
通讯作者：
Cohen T
影响因子：
4.2
作者：
Easey KE;Wootton RE;Sallis HM;Haan E;Schellhas L;Munafò MR;Timpson NJ;Zuccolo L
通讯作者：
Zuccolo L
DOI：
10.1016/j.socscimed.2018.07.035
发表时间：
2018-09
期刊：
Social science & medicine (1982)
影响因子：
--
作者：
Sharp GC;Lawlor DA;Richardson SS
通讯作者：
Richardson SS
DOI：
10.5534/wjmh.200147
发表时间：
2021-10
期刊：
The world journal of men's health
影响因子：
--
作者：
Montagnoli C;Ruggeri S;Cinelli G;Tozzi AE;Bovo C;Bortolus R;Zanconato G
通讯作者：
Zanconato G
影响因子：
2.9
作者：
Mamluk L;Edwards HB;Savović J;Leach V;Jones T;Moore THM;Ijaz S;Lewis SJ;Donovan JL;Lawlor D;Smith GD;Fraser A;Zuccolo L
通讯作者：
Zuccolo L