Effect of aging on cellular mechanotransduction.
Effect of aging on cellular mechanotransduction.
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DOI:
10.1016/j.arr.2009.11.002
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发表时间:
2011-01
影响因子:
13.1
通讯作者:
Blough, Eric R.
中科院分区:
文献类型:
--
作者:
Wu, Miaozong;Fannin, Jacqueline;Rice, Kevin M.;Wang, Bin;Blough, Eric R.
Aging is becoming a critical heath care issue and a burgeoning economic burden on society. Mechanotransduction is the ability of the cell to sense, process, and respond to mechanical stimuli and is an important regulator of physiologic function that has been found to play a role in regulating gene expression, protein synthesis, cell differentiation, tissue growth, and most recently, the pathophysiology of disease. Here we will review some of the recent findings of this field and attempt, where possible, to present changes in mechanotransduction that are associated with the aging process in several selected physiological systems, including musculoskeletal, cardiovascular, neuronal, respiratory systems and skin.
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影响因子:
--
作者:
BIALECKI, RA;KULIK, TJ;COLUCCI, WS
通讯作者:
COLUCCI, WS
DOI:
10.1126/stke.2002.119.pe6
发表时间:
2002-02-12
期刊:
Science's STKE : signal transduction knowledge environment
影响因子:
--
作者:
Alenghat, Francis J;Ingber, Donald E
通讯作者:
Ingber, Donald E
影响因子:
4.8
作者:
Carrino, DA;Önnerfjord, P;Caplan, AI
通讯作者:
Caplan, AI
影响因子:
0.9
作者:
Bittar, J.;Cepeda, P.;Massari, P. U.
通讯作者:
Massari, P. U.
影响因子:
4.5
作者:
Blough, E. R.;Rice, K. M.;Wright, G. L.
通讯作者:
Wright, G. L.