Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.
Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.
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DOI：
10.3389/fped.2021.647880
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发表时间：
2021
影响因子：
2.6
通讯作者：
Greisen G
中科院分区：
文献类型：
--
作者：
Rasmussen MI;Hansen ML;Pichler G;Dempsey E;Pellicer A;El-Khuffash A;A S;Piris-Borregas S;Alsina M;Cetinkaya M;Chalak L;Özkan H;Baserga M;Sirc J;Fuchs H;Ergenekon E;Arruza L;Mathur A;Stocker M;Otero Vaccarello O;Szczapa T;Sarafidis K;Królak-Olejnik B;Memisoglu A;Reigstad H;Rafińska-Ważny E;Hatzidaki E;Peng Z;Gkentzi D;Viellevoye R;De Buyst J;Mastretta E;Wang P;Hahn GH;Bender L;Cornette L;Tkaczyk J;Del Rio R;Fumagalli M;Papathoma E;Wilinska M;Naulaers G;Sadowska-Krawczenko I;Lecart C;Couce ML;Fredly S;Heuchan AM;Karen T;Greisen G
目的：评估在全球封锁期间，safebooc - iii联盟新生儿重症监护病房（nicu）收治的极早产（EP）婴儿（28周前出生）的数量与2019年同期相比是否存在差异。设计：这是一项回顾性观察性研究。来自17个国家的79个新生儿重症监护病房中的46个（58%）参与了调查。主要研究人员被要求报告以下信息：(1)新冠肺炎大流行第一阶段封锁最严格的3个月内新生儿重症监护病房收治的新生儿总数，(2)2019年相应3个月类似的新生儿入院人数，(3)封锁期间当地限制水平，(4)新冠肺炎封锁对当地孕妇日常生活的影响。结果：第一波COVID-19大流行期间EP婴儿入院人数为428人，而2019年相应的3个月为457人（- 6.6%，95% CI为- 18.2至+7.1%,p = 0.33）。在个别地理区域内没有统计学上的显著差异，封锁限制水平与EP婴儿入院人数的差异之间没有显著关联。基于46个新生儿重症监护病房数据的事后分析发现，新生儿重症监护病房入院总数减少了10.3%（2020年n = 7499人，2019年n = 8362人）。结论：这项临时研究并未证实之前关于COVID-19大流行第一阶段极早产数量大幅减少的报道。临床试验注册：ClinicalTrial.gov，标识符：NCT04527601（注册于2020年8月26日），https://clinicaltrials.gov/ct2/show/NCT04527601。
Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (−6.6%, 95% CI −18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.
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影响因子：
34.3
作者：
Ashish, K. C.;Gurung, Rejina;Malqvist, Mats
通讯作者：
Malqvist, Mats
影响因子：
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作者：
Philip RK;Purtill H;Reidy E;Daly M;Imcha M;McGrath D;O'Connell NH;Dunne CP
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Dunne CP
影响因子：
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作者：
Banerjee, Amitav;Chitnis, U B;Chaudhury, S
通讯作者：
Chaudhury, S
DOI：
10.1136/archdischild-2020-319990
发表时间：
2021-01-01
影响因子：
4.4
作者：
Hedermann, Gitte;Hedley, Paula Louise;Lausten-Thomsen, Ulrik
通讯作者：
Lausten-Thomsen, Ulrik
DOI：
10.1016/s2468-2667(20)30223-1
发表时间：
2020-11
期刊：
The Lancet. Public health
影响因子：
--
作者：
Been JV;Burgos Ochoa L;Bertens LCM;Schoenmakers S;Steegers EAP;Reiss IKM
通讯作者：
Reiss IKM