Neighborhood greenspace and neighborhood income associated with white matter grade worsening: Cardiovascular Health Study.
Neighborhood greenspace and neighborhood income associated with white matter grade worsening: Cardiovascular Health Study.
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DOI：
10.1002/dad2.12484
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发表时间：
2023-10
期刊：
影响因子：
--
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中科院分区：
文献类型：
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我们研究了社区绿地和社区中位数收入的联合测量是否与白色高信号（WMH）和心室大小变化相关。样本包括1260名认知正常的≥ 65岁的老年奥尔兹，他们有两次磁共振成像（MRI;间隔约5年）。WMH和心室大小从0（最小）到9（最大）分级为异常（恶化=从初始到随访MRI扫描增加≥1级）。四类邻里绿地收入指标是基于初始MRI时的邻里绿地和收入中值。多变量逻辑回归测试邻里绿地收入和MRI指标之间的关联（恶化与不恶化）。绿地面积较低、收入较低的社区比绿地面积较高、收入较高的社区更可能发生白色物质等级恶化（比值比= 1.73; 95%置信区间= 1.19-2.51）。较低的社区收入和较低的绿地可能是MRI上白色物质等级恶化的风险因素。然而，研究结果需要在更多样化的群体中复制。具有绿地和MRI数据的老年人（≥ 65岁）的基于人群的队列初始MRI MRI结局时社区绿地和社区收入的组合指标包括白色高信号（WMH）和心室大小MRI结局的纵向变化，测量间隔约5年WMH随时间的恶化更可能发生在绿地较低-收入较低的社区
We examined whether a combined measure of neighborhood greenspace and neighborhood median income was associated with white matter hyperintensity (WMH) and ventricle size changes. The sample included 1260 cognitively normal ≥ 65‐year‐olds with two magnetic resonance images (MRI; ≈ 5 years apart). WMH and ventricular size were graded from 0 (least) to 9 (most) abnormal (worsening = increase of ≥1 grade from initial to follow‐up MRI scans). The four‐category neighborhood greenspace–income measure was based on median neighborhood greenspace and income values at initial MRI. Multivariable logistic regression tested associations between neighborhood greenspace–income and MRI measures (worsening vs. not). White matter grade worsening was more likely for those in lower greenspace–lower income neighborhoods than higher greenspace–higher income neighborhoods (odds ratio = 1.73; 95% confidence interval = 1.19–2.51). The combination of lower neighborhood income and lower greenspace may be a risk factor for worsening white matter grade on MRI. However, findings need to be replicated in more diverse cohorts. Population‐based cohort of older adults (≥ 65 years) with greenspace and MRI data Combined measure of neighborhood greenspace and neighborhood income at initial MRI MRI outcomes included white matter hyperintensities (WMH) and ventricular size Longitudinal change in MRI outcomes measured approximately 5 years apart Worsening WMH over time more likely for lower greenspace‐lower income neighborhoods
白质高信号对老年人心室扩大的影响。
影响因子：
4.2
作者：
Jochems, Angela C. C.;Maniega, Susana Munoz;Hernandez, Maria del C. Valdes;Barclay, Gayle;Anblagan, Devasuda;Ballerini, Lucia;Meijboom, Rozanna;Wiseman, Stewart;Taylor, Adele M.;Corley, Janie;Chappell, Francesca M.;V. Backhouse, Ellen;Stringer, Michael S.;Dickie, David Alexander;Bastin, Mark E.;Deary, Ian J.;Cox, Simon R.;Wardlaw, Joanna M.
通讯作者：
Wardlaw, Joanna M.
影响因子：
13.6
作者：
Ma, Yuan;Sajeev, Gautam;VanderWeele, Tyler J.;Viswanathan, Anand;Sigurdsson, Sigurdur;Eiriksdottir, Gudny;Aspelund, Thor;Betensky, Rebecca A.;Grodstein, Francine;Hofman, Albert;Gudnason, Vilmundur;Launer, Lenore;Blacker, Deborah
通讯作者：
Blacker, Deborah