Association of leisure-time physical activity and sedentary behavior with carotid atherosclerosis morphology: The ARIC carotid-MRI study.
Association of leisure-time physical activity and sedentary behavior with carotid atherosclerosis morphology: The ARIC carotid-MRI study.
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休闲时间的体育锻炼与久坐行为与颈动脉粥样硬化形态的关联：Aric Carotid-MRI研究。
DOI：
10.1016/j.ajpc.2023.100505
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发表时间：
2023-06
影响因子：
4.1
通讯作者：
Palta, Priya
中科院分区：
文献类型：
--
作者：
Kumar, Aarti;Qiao, Ye;Wasserman, Bruce;Gabriel, Kelley Pettee;Martinez-Amezcua, Pablo;Dooley, Erin E;Diaz, Keith M;Evenson, Kelly R;Sharrett, A Richey;Zhang, Yiyi;Palta, Priya
我们评估了中年休闲时间体力活动（LTPA）和久坐行为（SB）及其时间模式与MRI测量的颈动脉粥样硬化形态的前瞻性关联。参与社区动脉粥样硬化风险（ARIC）研究的颈动脉MRI子研究（2004-2006），并在访视1（1987-1989）和3（1993-1995）时自我报告评估LTPA和SB的受试者被纳入本研究。使用ARIC/Baecke体力活动问卷确定LTPA，并根据美国心脏协会的不良，中等或理想体力活动指标进行分类。SB，衡量电视观看频率，分为高，中，低。我们使用多变量调整线性和逻辑回归模型来检查中年（仅访视3）和持续（访视1至3）LTPA和TV观看与颈动脉斑块负荷和组分之间的关联。在1，582名（平均年龄：59岁，43%男性，18%黑人）参与者中，分别有45.7%、21.7%和32.6%报告理想、中等或较差的LTPA。33.8%的参与者报告了高电视观看率，46.4%和19.8%的参与者分别报告了中等或低电视观看率。与较差的LTPA相比，中年理想的LTPA与总室壁容积无关（CI =0.01，95% CI：-0.01，0.03），最大颈动脉壁厚度标准化室壁指数（ROC =-0.01，95%CI：-0.03，0.01）或最大狭窄（ROC =-0.11，95%CI：-1.98，1.76）。与高水平相比，低水平或中等水平的看电视与颈动脉斑块负荷指标也不相关。与低LTPA或高TV观看相比，理想LTPA（比值比（OR）：0.82，95% CI：0.55，1.23）和低TV观看（OR=0.90，95% CI：0.56，1.44）分别与脂质核心存在的比值无关。总的来说，这项研究没有提供有力的证据证明LTPA和SB与颈动脉斑块测量之间的关联。
We evaluated the prospective association of midlife leisure-time physical activity (LTPA) and sedentary behavior (SB), and their temporal patterns, with MRI-measured carotid atherosclerotic morphology. Participants enrolled in the Carotid MRI substudy (2004–2006) of the Atherosclerosis Risk in Communities (ARIC) Study and with self-reported assessments of LTPA and SB at visits 1 (1987–1989) and 3 (1993–1995) were included in this study. LTPA was ascertained using the ARIC/Baecke physical activity questionnaire and categorized according to the American Heart Association's metric of poor, intermediate, or ideal physical activity. SB, measured as TV viewing frequency, was categorized as high, medium, and low. We used multivariable adjusted linear and logistic regression models to examine the associations between midlife (visit 3 only) and persistent (visit 1 to 3) LTPA and TV viewing with carotid artery plaque burden and components. Among the 1,582 (mean age: 59 years, 43% male, 18% Black) participants, 45.7%, 21.7%, and 32.6% reported ideal, intermediate, or poor LTPA, respectively. High TV viewing was reported in 33.8% of participants, with 46.4% and 19.8% reporting medium or low TV viewing, respectively. Compared to poor LTPA, ideal LTPA in midlife was not associated with total wall volume (ß=0.01, 95% CI: -0.01, 0.03), maximum carotid wall thickness (ß=0.06, 95% CI: -0.08, 0.21), normalized wall index (ß=-0.01, 95% CI: -0.03, 0.01), or maximum stenosis (ß=-0.11, 95% CI: -1.98, 1.76). Low or middle, compared to high, TV viewing was also not associated with carotid artery measures of plaque burden. Compared to poor LTPA or high TV viewing, ideal LTPA (odds ratio (OR): 0.82, 95% CI: 0.55, 1.23) and low TV viewing (OR=0.90, 95% CI: 0.56, 1.44) was not associated with odds of lipid core presence, respectively. Overall, this study does not provide strong evidence for an association between LTPA and SB with carotid plaque measures.
影响因子：
6.3
作者：
Barrett-Connor E;Bergstrom J;Wright M;Kramer CK
通讯作者：
Kramer CK