Single unit activity in the rat superior colliculus during reward magnitude task performance.

Single unit activity in the rat superior colliculus during reward magnitude task performance.
复制标题

在奖励幅度任务执行期间大鼠上丘的单个单位活动。

DOI:
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发表时间:
2008
影响因子:
1.9
通讯作者:
Avery A. Rizio
Avery A. Rizio
中科院分区:
医学4区
文献类型:
--
作者:
D. A. Weldon;Carlyn A. Patterson;Erica A Colligan;C. Nemeth;Avery A. Rizio

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Long-Evans兜帽大鼠被训练在t型迷宫中运行一种交替模式:一只手臂的食物杯中有低奖励(1粒),另一只手臂的食物杯中有高奖励(3粒)。使用可移动微电极记录上丘中间和深层的单个单元。大多数单位显示出与食物获取有关的活动,在停止跑步或将鼻子插入食物杯时,活动会阶段性地增加。一些单元(16%)在获取两种量级的奖励时表现出不同的活动模式。虽然70%的单元表现出单峰或多峰的感觉敏感性,通常是对鼻子的触觉刺激的反应,但这种特性与食物获取相关的活动无关。这些数据支持了之前的观察,即大鼠SC中的细胞表现出与食物获取相关的活动,并表明其中一些神经元的编码反映了奖励刺激的特征。
Long-Evans hooded rats were trained to run an alternation pattern in a t-maze with low reward (1 pellet) in the food cup of one arm and high reward (3 pellets) in the food cup of the other arm. Single units in the intermediate and deep layers of the superior colliculus were recorded using moveable microelectrodes. Most units showed activity that was associated with food retrieval, with a phasic increase in activity either upon the cessation of running or upon the insertion of the snout into the food cup. Some units (16%) showed different activity patterns upon retrieval of the two magnitudes of reward. Although 70% of the units showed either unimodal or multimodal sensory sensitivity, usually in response to tactile stimulation of the snout, this property was not related to activity associated with food retrieval. These data support previous observations that cells in the rat SC exhibit activity related to food retrieval, and indicate that for some of these neurons the coding reflects the characteristics of the reward stimulus.
DOI: 10.1037/0735-7044.112.3.554
发表时间: 1998-06-01
影响因子: 1.9
作者:
Pratt, WE;Mizumori, SJY
通讯作者: Mizumori, SJY