Advances in Diagnostic Imaging for Cardiac Sarcoidosis.

Advances in Diagnostic Imaging for Cardiac Sarcoidosis.
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DOI:
10.3390/jcm10245808
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发表时间:
2021-12-11
影响因子:
3.9
通讯作者:
Tamaki N
Tamaki N
中科院分区:
医学2区
文献类型:
--
作者:
Manabe O;Oyama-Manabe N;Aikawa T;Tsuneta S;Tamaki N

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结节病是一种病因不明的全身性肉芽肿性疾病,其临床表现取决于受累器官。心脏结节病(CS)是结节病患者死亡的主要原因之一。由于心肌中肉芽肿性炎症的程度和位置,CS的临床表现是异质性的,并且范围从无症状到危及生命的心律失常和进行性心力衰竭。由于心肌活检的组织学诊断敏感性较低,因此影像学技术的进步在冠状动脉综合征的评价中发挥了关键作用。CS的诊断具有挑战性,并且已经报道了几种方法,特别是使用正电子发射断层扫描和心脏磁共振成像(MRI)的方法。延迟增强计算机断层扫描(CT)也可用于诊断MRI不兼容器械患者的CS,并可对此类患者的心肌增强进行可接受的评价。本文就CS影像学检查的进展作一综述。
Sarcoidosis is a systemic granulomatous disease of unknown etiology, and its clinical presentation depends on the affected organ. Cardiac sarcoidosis (CS) is one of the leading causes of death among patients with sarcoidosis. The clinical manifestations of CS are heterogeneous, and range from asymptomatic to life-threatening arrhythmias and progressive heart failure due to the extent and location of granulomatous inflammation in the myocardium. Advances in imaging techniques have played a pivotal role in the evaluation of CS because histological diagnoses obtained by myocardial biopsy tend to have lower sensitivity. The diagnosis of CS is challenging, and several approaches, notably those using positron emission tomography and cardiac magnetic resonance imaging (MRI), have been reported. Delayed-enhanced computed tomography (CT) may also be used for diagnosing CS in patients with MRI-incompatible devices and allows acceptable evaluation of myocardial hyperenhancement in such patients. This article reviews the advances in imaging techniques for the evaluation of CS.
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