Neural representation of three-dimensional acoustic space in the human temporal lobe.

Neural representation of three-dimensional acoustic space in the human temporal lobe.
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人类颞叶三维声学空间的神经表征

DOI:
10.3389/fnhum.2015.00203
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发表时间:
2015
影响因子:
2.9
通讯作者:
Zhang B
Zhang B
中科院分区:
医学3区
文献类型:
--
作者:
Zhang X;Zhang Q;Hu X;Zhang B

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声音定位是人脑的一项重要功能,但其皮层机制尚不清楚。在这项研究中,我们记录了三维空间中的听觉刺激,然后在功能磁共振成像(fMRI)过程中通过耳机重放刺激。通过采用机器学习算法,我们成功地从颞叶中的血氧水平依赖信号中解码出声音位置。数据分析表明,不同的皮质模式引起的声音从不同的位置。具体地说,声音位置沿着横坐标轴的歧视引起的强大的反应,在左后颞上回(STG)和右中STG,歧视沿着(EL)轴引起的强大的反应,在左后中颞叶(MTL)和右STG,歧视沿着纵坐标轴引起的强大的反应,在左中MTL和右中STG。这些结果支持了人类皮层中声学空间的分布式表示。
Sound localization is an important function of the human brain, but the underlying cortical mechanisms remain unclear. In this study, we recorded auditory stimuli in three-dimensional space and then replayed the stimuli through earphones during functional magnetic resonance imaging (fMRI). By employing a machine learning algorithm, we successfully decoded sound location from the blood oxygenation level-dependent signals in the temporal lobe. Analysis of the data revealed that different cortical patterns were evoked by sounds from different locations. Specifically, discrimination of sound location along the abscissa axis evoked robust responses in the left posterior superior temporal gyrus (STG) and right mid-STG, discrimination along the elevation (EL) axis evoked robust responses in the left posterior middle temporal lobe (MTL) and right STG, and discrimination along the ordinate axis evoked robust responses in the left mid-MTL and right mid-STG. These results support a distributed representation of acoustic space in human cortex.
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