The P300 Auditory Event-Related Potential May Predict Segregation of Competing Speech by Bimodal Cochlear Implant Listeners.
The P300 Auditory Event-Related Potential May Predict Segregation of Competing Speech by Bimodal Cochlear Implant Listeners.
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P300听觉事件相关的潜力可能预测双峰人耳蜗植入者听众竞争语音的隔离。
DOI：
10.3389/fnins.2022.888596
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发表时间：
2022
影响因子：
4.3
通讯作者：
Liu, Ji-Sheng
中科院分区：
文献类型：
--
作者：
Tao, Duo-Duo;Zhang, Yun-Mei;Liu, Hui;Zhang, Wen;Xu, Min;Galvin, John J., III;Zhang, Dan;Liu, Ji-Sheng
与正常听力（NH）的听众相比，人工耳蜗（CI）的听众有更大的困难分离竞争的讲话。神经生理学研究主要是利用事件相关电位（ERPs）的P300成分来探讨安静条件下CI听者言语识别的神经基础。P300与听觉辨别、选择性注意和工作记忆等认知过程密切相关。与安静环境下的言语感知不同，CI听者对竞争言语的分离的神经生理学基础知之甚少。在这项研究中，ERPs测量了11名普通话双模态CI听众和11名NH听众的1与2 kHz的对比。在稳态噪声中或在男性或女性掩蔽声中测量男性目标说话者的言语接收阈值（SRT）。结果显示，NH组P300波幅显著大于CI组，潜伏期显著短于CI组。同样，NH组的SRT显著优于CI组。在所有参与者中，P300振幅与稳态噪声中的SRT（r =-0.65，p = 0.001）以及与竞争性男性（r =-0.62，p = 0.002）和女性掩蔽者（r =-0.60，p = 0.003）显著相关。在CI组中，P300振幅和SRT与男性掩蔽者之间存在显著相关性（r =-0.78，p = 0.005），这产生了最多的信息掩蔽。结果表明，P300振幅可能是临床上有用的中枢听觉处理能力（例如，对信息掩蔽的易感性）。
Compared to normal-hearing (NH) listeners, cochlear implant (CI) listeners have greater difficulty segregating competing speech. Neurophysiological studies have largely investigated the neural foundations for CI listeners' speech recognition in quiet, mainly using the P300 component of event-related potentials (ERPs). P300 is closely related to cognitive processes involving auditory discrimination, selective attention, and working memory. Different from speech perception in quiet, little is known about the neurophysiological foundations for segregation of competing speech by CI listeners. In this study, ERPs were measured for a 1 vs. 2 kHz contrast in 11 Mandarin-speaking bimodal CI listeners and 11 NH listeners. Speech reception thresholds (SRTs) for a male target talker were measured in steady noise or with a male or female masker. Results showed that P300 amplitudes were significantly larger and latencies were significantly shorter for the NH than for the CI group. Similarly, SRTs were significantly better for the NH than for the CI group. Across all participants, P300 amplitude was significantly correlated with SRTs in steady noise (r = −0.65, p = 0.001) and with the competing male (r = −0.62, p = 0.002) and female maskers (r = −0.60, p = 0.003). Within the CI group, there was a significant correlation between P300 amplitude and SRTs with the male masker (r = −0.78, p = 0.005), which produced the most informational masking. The results suggest that P300 amplitude may be a clinically useful neural correlate of central auditory processing capabilities (e.g., susceptibility to informational masking) in bimodal CI patients.
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DOI：
10.1121/1.4954748
发表时间：
2016-07
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Kidd G Jr;Mason CR;Swaminathan J;Roverud E;Clayton KK;Best V
通讯作者：
Best V
影响因子：
1.1
作者：
Grasel, Signe;Greters, Mario;Bento, Ricardo Ferreira
通讯作者：
Bento, Ricardo Ferreira
影响因子：
1.6
作者：
Henkin, Yael;Tetin-Schneider, Simona;Kishon-Rabin, Liat
通讯作者：
Kishon-Rabin, Liat
影响因子：
1.1
作者：
Calderaro, Victor Goiris;Amaral, Maria Stella Arantes do;Reis, Ana Claudia Mirândola Barbosa
通讯作者：
Reis, Ana Claudia Mirândola Barbosa
影响因子：
3.7
作者：
Crew JD;Galvin JJ 3rd;Landsberger DM;Fu QJ
通讯作者：
Fu QJ