Understanding Ocular Findings and Manifestations of Systemic Lupus Erythematosus: Update Review of the Literature.

Understanding Ocular Findings and Manifestations of Systemic Lupus Erythematosus: Update Review of the Literature.
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DOI:
10.3390/ijms232012264
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发表时间:
2022-10-14
影响因子:
5.6
通讯作者:
--
中科院分区:
生物学2区
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--
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系统性红斑狼疮(SLE)是一种慢性多系统自身免疫性疾病。多达三分之一的SLE患者有各种眼部表现。眼部表现可能代表全身性疾病的最初表现,并可能导致严重的眼部并发症,甚至丧失视力。眼部表现常与全身性炎症程度有关,但也可先于全身性症状的发生。SLE患者的早期诊断和适当的管理是至关重要的,需要各专家的合作。眼科医生的适当准备有助于区分SLE并发症和其他眼部疾病。SLE的新疗法有望带来潜在的益处,然而,眼部副作用仍然未知。
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease. Up to one-third of patients suffering from SLE have various ocular manifestations. The ocular findings may represent the initial manifestation of the systemic disease and may lead to severe ocular complications, and even loss of vision. Ocular manifestations are often associated with degree of systemic inflammation, but also can precede the occurrence of systemic symptoms. Early diagnosis and adequate management of patients with SLE are crucial and require cooperation between various specialists. Proper preparation of ophthalmologists can help to differentiate between complication of SLE and other ocular disorders. New therapies for SLE are promising for potential benefits, however, ocular side effects are still unknown.
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