Specific detection of Epstein-Barr virus in inflammatory pseudotumor of the spleen in a patient with a high serum level of soluble IL-2 receptor
Specific detection of Epstein-Barr virus in inflammatory pseudotumor of the spleen in a patient with a high serum level of soluble IL-2 receptor
复制标题
血清可溶性IL-2受体高水平患者脾脏炎性假瘤中Epstein-Barr病毒的特异性检测
DOI：
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发表时间：
2000
影响因子：
6.3
通讯作者：
K. Kumada
中科院分区：
文献类型：
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作者：
M. Yamaguchi;Takako Yamamoto;G. Tate;Tadashi Matsumoto;A. Matsumiya;M. Kuzume;Y. Sanada;K. Kumada
摘要：报道了一例脾脏炎性假瘤病例，患者为一名63岁女性，患有脾内肿瘤，血清可溶性白细胞介素2受体（sIL-2 R）水平升高。切除脾脏后的显微镜检查显示肿瘤由混合细胞浸润组成，主要是淋巴细胞和浆细胞，以及梭形细胞增殖。EB病毒（EBV）特异性检测肿瘤中的EBV RNA的原位杂交。脾切除后血清sIL-2 R水平恢复正常。EBV感染可能参与了脾炎性假瘤的发生和sIL-2 R水平的升高。
Abstract: A case of inflammatory pseudotumor of the spleen is described in a 63-year-old woman who presented with an intrasplenic tumor and an elevated serum level of soluble interleukin 2 receptor (sIL-2R). Microscopic examination after removal of the spleen revealed that the tumor was composed of mixed cellular infiltrates, mainly lymphocytes and plasma cells, and spindle-cell proliferation. Epstein-Barr virus (EBV) was specifically detected in the tumor by in situ hybridization for EBV RNA. The serum level of sIL-2R level was normalized after splenectomy. EBV infection may play a role in the development of splenic inflammatory pseudotumor and the elevation of sIL-2R level.
影响因子：
3.3
作者：
ARBER, DA;KAMEL, OW;WEISS, LM
通讯作者：
WEISS, LM
恶性淋巴瘤患者的可溶性白介素 2 受体。
影响因子：
4.6
作者：
Harrington,DS;Patil,K;Lai,PK;Yasuda,NN;Armitage,JO;Ip,SH;Weisenburger,DD;Linder,J;Purtilo,DT
通讯作者：
Purtilo,DT