Spatial and episodic memory tasks promote temporal lobe interictal spikes

Spatial and episodic memory tasks promote temporal lobe interictal spikes
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空间和情景记忆任务促进颞叶发作间期尖峰

DOI:
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发表时间:
2019
影响因子:
11.2
通讯作者:
M. Walker
M. Walker
中科院分区:
医学1区
文献类型:
--
作者:
U. Vivekananda;D. Bush;J. Bisby;B. Diehl;A. Jha;P. Nachev;R. Rodionov;N. Burgess;M. Walker

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反射性癫痫已被证明利用特定的网络,使正常的生理功能。目前还不清楚是否有更多常见的癫痫病也具有这种特殊的特征。通过测量一系列癫痫患者的发作间期尖峰,我们发现,2个已知的任务,专门从事海马和颞叶新皮层促进增加这些区域内的发作间期尖峰,而nonhippocampal依赖的任务没有。这表明,发作间期的尖峰频率可能反映了特定的功能解剖网络在癫痫的处理要求。神经网络2019;86:304-309
Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to specifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within these regions, whereas a nonhippocampal dependent task did not. This indicates that interictal spike frequency may reflect the processing demands being placed on specific functional–anatomical networks in epilepsy. ANN NEUROL 2019;86:304–309
DOI: 10.1093/brain/awt159
发表时间: 2013-08-01
期刊: BRAIN
影响因子: 14.5
作者:
Matsumoto, Joseph Y.;Stead, Matt;Worrell, Gregory A.
通讯作者: Worrell, Gregory A.