Respiratory cycle-related EEG changes during sleep reflect esophageal pressures.
Respiratory cycle-related EEG changes during sleep reflect esophageal pressures.
复制标题
睡眠期间与呼吸周期相关的脑电图变化反映了食管压力。
DOI:
10.1093/sleep/31.12.1713
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发表时间:
2008
期刊:
影响因子:
5.6
通讯作者:
Burns,JosephW
中科院分区:
文献类型:
--
作者:
Chervin,RonaldD;Malhotra,RamanK;Burns,JosephW
Study ObjectivesRespiratory cycle-related EEG changes (RCREC) have been demonstrated during sleep by digital analysis and hypothesized to represent subtle inspiratory microarousals that may help to explain daytime sleepiness in patients with sleep-disordered breathing. We therefore examined for the first time associations between RCREC and esophageal pressure swings (ΔPes) that reflect work of breathing.DesignRetrospective analysisSettingAcademic sleep laboratoryPatientsForty adults referred for suspected sleep disordered breathingInterventionsPolysomnography with esophageal pressure monitoring and automatic computation of ΔPes using a novel algorithm.ResultsComputed ΔPes for nearly all respiratory cycles during sleep correlated well with visual scoring of selected respiratory cycle samples (Spearmanrho= 0.86, P < 0.0001). The RCREC within the sigma EEG range (12.5–15.5 Hz) rather than that within other frequency ranges most often showed significant within-subject inverse correlations with ΔPes. In contrast, in between-subject comparisons, beta (15.5–30.5 Hz) and to a lesser extent theta (4.5–7.5 Hz) RCREC, rather than sigma RCREC, showed significant inverse associations with mean ΔPes.ConclusionsVariation within subjects of sigma RCREC with ΔPes supports previous evidence that RCREC within this range may reflect microarousals exacerbated by increased work of breathing. Correlation of beta and theta, but not sigma RCREC with ΔPes in between-subject comparisons is more difficult to explain but suggests that ranges other than sigma also deserve further investigation for clinical utility.
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影响因子:
5.6
作者:
Chervin, RD;Burns, JW;Ruzicka, DL
通讯作者:
Ruzicka, DL
影响因子:
5.6
作者:
R. Chervin;Deborah L. Ruzicka;Judith L Wiebelhaus;Garnett L Hegeman;Deanna J. Marriott;C. Marcus;B. Giordani;R. Weatherly;James E. Dillon
通讯作者:
James E. Dillon
影响因子:
5.6
作者:
Chervin,RD;Aldrich,MS
通讯作者:
Aldrich,MS
影响因子:
24.7
作者:
R. Chervin;J. W. Burns;Deborah L. Ruzicka
通讯作者:
Deborah L. Ruzicka
影响因子:
9.6
作者:
GUILLEMINAULT, C;STOOHS, R;MAISTROS, P
通讯作者:
MAISTROS, P